Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin. [PDF]
, 2017 Gene silencing by heterochromatin is proposed to occur in part as a result of the ability of heterochromatin protein 1 (HP1) proteins to spread across large regions of the genome, compact the underlying chromatin and recruit diverse ligands.
Agard, David A +8 more
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Polymer-stabilized sialylated nanoparticles : synthesis, optimization, and differential binding to influenza hemagglutinins [PDF]
, 2020 During influenza infection, hemagglutinins (HAs) on the viral surface bind to sialic acids on the host cell's surface. While all HAs bind sialic acids, human influenza targets terminal α2,6 sialic acids and avian influenza targets α2,3 sialic acids.
Baker, Alexander +3 more
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Factors That Govern the Induction of Long-Lived Antibody Responses
Viruses, 2020 The induction of long-lasting, high-titer antibody responses is critical to the efficacy of many vaccines. The ability to produce durable antibody responses is governed by the generation of the terminally differentiated antibody-secreting B cells known ...
Bryce Chackerian, David S. Peabody
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Molecules, 2021 Among carbohydrate-processing enzymes, Jack bean α-mannosidase (JBα-man) is the glycosidase with the best responsiveness to the multivalent presentation of iminosugar inhitopes.
Costanza Vanni +9 more
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The Symmetry of Viral Sialic Acid Binding Sites–Implications for Antiviral Strategies
Viruses, 2019 Virus infections are initiated by the attachment of the viral particle to protein or carbohydrate receptors on the host cell. Sialic acid-bearing glycan structures are prominently displayed at the cell surface, and, consequently, these structures can ...
Nils H. Rustmeier +2 more
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Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction [PDF]
, 2019 © The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Kim, S., Kalappurakkal, J. M., Mayor, S., & Rosen, M. K.
Kalappurakkal, Joseph Mathew +3 more
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Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment [PDF]
, 2020 Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes.
Ashree, Jayshree, Chao, Yimin, Wang, Qi
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Multivalent Aptamers: Versatile Tools for Diagnostic and Therapeutic Applications
Molecules, 2016 Nucleic acid aptamers generated through an in vitro selection are currently extensively applied as very valuable biomolecular tools thanks to their prominent advantages. Diversity of spatial structures, ease of production through chemical synthesis and a
Mariya Vorobyeva +2 more
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On Certain Multivalent Functions [PDF]
International Journal of Mathematics and Mathematical Sciences, 2007 Let𝒮*(p,α)be the class of functionsf(z)which are analytic andp-valently starlike of orderαin the open unit diskE. The object of the present paper is to derive an interesting condition forf(z)to be in the class𝒮*(p,α).
Mamoru Nunokawa +5 more
openaire +3 more sources
Lewis X antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-Type lectin [PDF]
, 2007 Lewis x (Lex, CD15), also known as SSEA-1 (stage specific embryonic antigen-1), is a trisaccharide with the structure Galβ(1–4)Fucα(1–3)GlcNAc, which is expressed on glycoconjugates in human polymorphonuclear granulocytes and various tumors such as colon
A Hittelet +51 more
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