Results 171 to 180 of about 24,310,597 (280)

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Research on the surface water quality in the Huaihe River Basin and the gensis based on multivariate statistical analysis. [PDF]

Sci Rep
Feng S, Zhang C, Yan J, Ren K, Peng N, Jiang W, Liu S.   +6 more
europepmc   +1 more source

Combining Contamination Indices and Multivariate Statistical Analysis for Metal Pollution Evaluation during the Last Century in Lacustrine Sediments of Lacu Sărat Lake, Romania. [PDF]

Int J Environ Res Public Health, 2023
Ganea IV, Bălc R, Begy RC, Tanțău I, Gligor DM.   +4 more
europepmc   +1 more source

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source

Identification of Key Aroma Substances in Pomegranate from Different Geographical Origins via Integrated Volatile Profiling and Multivariate Statistical Analysis. [PDF]

Foods
Zhang Y, Guo W, Qu H, Zhang L, Liu L, Hu X, Liu Y.   +6 more
europepmc   +1 more source

Insights into the Aroma Profile of Sauce-Flavor Baijiu by GC-IMS Combined with Multivariate Statistical Analysis. [PDF]

J Anal Methods Chem, 2022
Cai W, Wang Y, Wang W, Shu N, Hou Q, Tang F, Shan C, Yang X, Guo Z.   +8 more
europepmc   +1 more source

Systematic Position Mapping of Split CRISPR‐Cas12a Activators Enables Highly Sensitive miRNA Detection and Cancer Cell Stratification

Advanced Science, EarlyView.
ABSTRACT Amplification‐free Cas12a diagnostics with split crRNA enable rapid and programmable target recognition, yet insufficient understanding of DNA activator architecture prevents predictable control over trans‐cleavage activity and sensitivity. Here we systematically map over 200 split DNA activator configurations by introducing nicks at every ...
Xiaoyan Tang, Zhe Li, Yuning Lu, Miao Ma, Zijian Mo, Jiajun Ke, Xinyu Luan, Tiangang Luan, Junqiu Zhai   +8 more
wiley   +1 more source

Other title: Office of Criminal Justice Services research brief; Other title: Bulletin of the Ohio Statistical Analysis Center

, 2012
Irregular; Began with: Volume 1, Issue 1 (April 2012).; Subtitle varies: "Quarterly bulletin of the Ohio Statistical Analysis Center," April 2012; "A bulletin of the Ohio Statistical Analysis Center," September 2012-; Harvested from the web on 1/6 ...
Ohio Statistical Analysis Center,
core  

Radioactivity distribution and concomitant hazards evaluation of industrial zones soils from Chattogram, Bangladesh: A multivariate statistical analysis. [PDF]

PLoS One
Siraz MMM, Islam S, Shelley A, Alam MS, Mahmud A, Rashid MB, Khandaker MU, Yeasmin S, Rahman MS.   +8 more
europepmc   +1 more source

No ambiguity: Chemosensory-based ayurvedic classification of medicinal plants can be fingerprinted using E-tongue coupled with multivariate statistical analysis. [PDF]

Front Pharmacol, 2022
Jayasundar R, Ghatak S, Kumar D, Singh A, Bhosle P.   +4 more
europepmc   +1 more source