Advanced Science, EarlyView.In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang +6 more
wiley +1 more source
Simulation Experiments in Practice: Statistical Design and Regression Analysis [PDF]
In practice, simulation analysts often change only one factor at a time, and use graphical analysis of the resulting Input/Output (I/O) data. Statistical theory proves that more information is obtained when applying Design Of Experiments (DOE) and linear
Kleijnen, J.P.C.
core
Investigating potential freshness indicators for packaged oysters through multivariate statistical analysis. [PDF]
Food Sci BiotechnolPark SK +6 more
europepmc +1 more source
Characterization and Discrimination of Ophiopogonis Radix with Different Levels of Sulfur Fumigation Based on UPLC-QTOF-MS Combined Molecular Networking with Multivariate Statistical Analysis. [PDF]
Metabolites, 2023 Lv Y +9 more
europepmc +1 more source
Advanced Science, EarlyView.An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang +15 more
wiley +1 more source
A Comprehensive Evaluation of Nutritional Quality and Antioxidant Capacity of Different Chinese Eggplant Varieties Based on Multivariate Statistical Analysis. [PDF]
Antioxidants (Basel)Lyu J +7 more
europepmc +1 more source
The Difference of Volatile Compounds in Female and Male Buds of Trichosanthes anguina L. Based on HS-SPME-GC-MS and Multivariate Statistical Analysis. [PDF]
Molecules, 2022 Song P, Xu B, Liu Z, Cheng Y, Chao Z.
europepmc +1 more source
Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Advanced Science, EarlyView.Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
wiley +1 more source
Multivariate statistical analysis of quality traits in 70 oat germplasm resources
Siliao yanjiuThe experiment aimed to systematically evaluate the genetic diversity of quality traits in 70 oat germplasm resources, screen elite germplasm, and clarify the correlation patterns among core quality indicators.
ZHUANG Xu +7 more
doaj
Seasonal assessment of surface water and sediments pollution in Rachiine River, Northern Lebanon, using multivariate statistical analysis. [PDF]
HeliyonMansour R +3 more
europepmc +1 more source