Results 131 to 140 of about 3,415 (314)

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

MEDIANDO UMA CULTURA DE NÃO-VIOLÊNCIA: a municipalização da medida de liberdade assistida na integração social do adolescente em conflito com a lei

Revista de Políticas Públicas, 2009
The study aims to analyze public policies to face urban violence. It interprets the phenomenon as a result of objective factors, such as social inequality and the failure of the punishment system and of subjective reasons such as the consumption, culture
Sidnéia Bento Duque
doaj  

Организационно-экономический механизм управления социальной инфраструктурой промышленного предприятия [PDF]

, 2014
У статті досліджуються особливості управління соціальною інфраструктурою промислових підприємств та можливості досягнення ефективності закладів соціальної інфраструктури за різними складовими.
Letunovska, Nataliia Yevhenіvna, Tielietov, Oleksandr Serhiiovych, Летуновская, Наталия Евгеньевна, Летуновська, Наталія Євгенівна, Телетов, Александр Сергеевич, Тєлєтов, Олександр Сергійович   +5 more
core  

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Norwegian Shelters for Victims of Domestic Violence in the COVID-19 Pandemic - Navigating the New Normal. [PDF]

J Fam Violence, 2022
Bergman S, Bjørnholt M, Helseth H.
europepmc   +1 more source

Municipal Observatories [PDF]

Science, 1921
openaire   +2 more sources

To Divest or not to Divest? Social Assets in Russian Firms [PDF]

, 2004
In the planned economy firms were made responsible for providing their workers with social services, such as housing, day care and medical care. In the transforming Russia of the 1990s, social assets were to be transferred from industrial enterprises to ...
Juurikkala, Tuuli, Lazareva, Olga
core  

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Does public ownership of utilities matter for local government water policies? [PDF]

Util Policy, 2020
Homsy GC, Warner ME.
europepmc   +1 more source

Teacher Training in Chile: Where Are Universities Looking? A Narrative Review. [PDF]

Int J Environ Res Public Health, 2022
Castillo-Paredes A, Núñez-Valdés K, Villegas Dianta C, Villena Olivares N, López Núñez M, Fuentes-Rubio M, Núñez-Valdés G.   +6 more
europepmc   +1 more source