Results 11 to 20 of about 2,758 (169)

Kv2 channels do not function as canonical delayed rectifiers in spinal motoneurons. [PDF]

iScience
Summary: The increased muscular force output required for some behaviors is achieved via amplification of motoneuron output via cholinergic C-bouton synapses.
Smith CC, Nascimento F, Özyurt MG, Beato M, Brownstone RM.   +4 more
europepmc   +2 more sources

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation. [PDF]

Angew Chem Int Ed Engl
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Dörner S, Rogge K, Trottmann F, Hertweck C, Hoffmeister D.   +4 more
europepmc   +3 more sources

Cholecystokinin Induces Ca²⁺ Transients in Brainstem Neurons, Astrocytes and Central Vagal Terminals in Jugular/Nodose Ganglia-Brainstem Slice Cultures. [PDF]

Eur J Neurosci
A jugular/nodose ganglion–brainstem slice culture with intact ganglia attached to the brainstem, preserving functional vagal afferent pathways to the brainstem. In this preparation, cholecystokinin activates brainstem neurons, central vagal terminals and brainstem astrocytes, establishing this preparation as a powerful model for dissecting the neuro ...
Ujhelyi A, Kucharz RS, Rekling JC.
europepmc   +2 more sources

Mycotoxins in Basidiomycete Mycelium and Fruiting Bodies: Implications for Eu Novel Food Assessment and Selected International Regulatory Frameworks. [PDF]

Compr Rev Food Sci Food Saf
ABSTRACT Advances in technology have enabled the efficient and sustainable production of basidiomycete vegetative mycelium, particularly from Pleurotus species, as a novel food source. However, mycelium has yet to receive regulatory approval in many global markets, requiring a better understanding of factors affecting its safety.
Berglund NEW, Lankinen PV, Mikkonen KS.
europepmc   +2 more sources

Two new Inosperma (Inocybaceae) species with unexpected muscarine contents from tropical China [PDF]

MycoKeys, 2021
An accurate identification of poisonous mushrooms and the confirmation of the toxins involved are both of great importance in the treatment of mushroom poisoning incidents. In recent years, cases of mushroom poisoning by Inosperma spp.
Lun-Sha Deng, Rui Kang, Nian-Kai Zeng, Wen-Jie Yu, Cheng Chang, Fei Xu, Wang-Qiu Deng, Liang-Liang Qi, Yu-Ling Zhou, Yu-Guang Fan   +9 more
doaj   +3 more sources

Effective Treatment With Olanzapine for Burning Mouth Syndrome With Denture Intolerance in an Older Patient: A Case Report. [PDF]

Gerodontology
ABSTRACT Introduction Burning mouth syndrome (BMS) is occasionally accompanied by denture intolerance. Case Presentation An 80‐year‐old woman with complaints of residual and relapsed intraoral pain and denture intolerance due to BMS was improved by olanzapine without severe adverse events, and her eating ability was successfully restored.
Watanabe M, Inokoshi M, Maeda C, Takao C, Tominaga R, Kimura Y, Nagamine T, Toyofuku A.   +7 more
europepmc   +2 more sources

Combined Effects of Intermittent Hypoxia and Amyloid Beta on Hippocampal Activity, Its Cholinergic Modulation, and Memory. [PDF]

Hippocampus
ABSTRACT Obstructive sleep apnea (OSA), characterized by repetitive upper airway obstruction, leads to chronic intermittent hypoxia (cIH) and induces cognitive and neuronal network disruptions similar to those observed in Alzheimer's disease (AD). These pathologies are often presented together in the elderly and share some pathophysiological mechanisms.
Pinedo-Vargas L, Méndez-Salcido F, Lorea-Hernández JJ, de Lafuente V, Peña-Ortega F.   +4 more
europepmc   +2 more sources

Five new species of Inosperma from China: Morphological characteristics, phylogenetic analyses, and toxin detection

Frontiers in Microbiology, 2022
Many species of Inosperma cause neurotoxic poisoning in humans after consumption around the world. However, the toxic species of Inosperma and its toxin content remain unclear.
Sai-Nan Li, Fei Xu, Pan Long, Feng Liu, Ping Zhang, Yu-Guang Fan, Zuo-Hong Chen   +6 more
doaj   +1 more source

A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China

Frontiers in Microbiology, 2022
Currently, mushroom poisoning still poses a huge problem to humans' health and life globally. Poisoning incidents caused by Inosperma spp. were reported continuously in tropical China in recent years.
Lun-Sha Deng, Wen-Jie Yu, Nian-Kai Zeng, Yi-Zhe Zhang, Xiao-Peng Wu, Hai-Jiao Li, Fei Xu, Yu-Guang Fan   +7 more
doaj   +1 more source

Amanita muscaria: Ecology, Chemistry, Myths

Encyclopedia, 2021
Amanita muscaria is the most emblematic mushroom in the popular representation. It is an ectomycorrhizal fungus endemic to the cold ecosystems of the northern hemisphere.
Quentin Carboué, Michel Lopez
doaj   +1 more source