Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons
The muscarinic acetylcholine receptor (mAChR) antagonist, scopolamine, has been shown to have a rapid antidepressant effect. And it is believed that GABAergic interneurons play a crucial role in this action.
Huanxin Chen +14 more
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Two new toxic yellow Inocybe species from China: morphological characteristics, phylogenetic analyses and toxin detection [PDF]
Some species of Inocybe s. str. caused neurotoxic poisoning after consumption around the world. However, there are a large number of species in this genus that have not been studied for their toxicity or toxin content.
Sai Nan Li +7 more
doaj +3 more sources
Pseudosperma arenarium (Inocybaceae), a new poisonous species from Eurasia, based on morphological, ecological, molecular and biochemical evidence [PDF]
In this study, Pseudosperma arenarium is proposed as a new species, based on morphological, ecological, molecular and biochemical evidence. The new species grows on sandy ground under Populus and Pinus sylvestris in north-western China and northern ...
Ya-Ya Yan +6 more
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Seven Newly Recorded Macrofungi of Inocybaceae (Agaricales, Basidiomycota) in Korea
The Inocybaceae is a family of ectomycorrhizal fungi belonging to the Agaricales order. Most species in this family produce secondary metabolites, such as muscarine, psilocybin, and other compounds. In the present study, we conducted taxonomic studies on
Sung-Eun Cho +3 more
doaj +1 more source
Successful cholinergic-noradrenergic pharmacotherapy for obstructive sleep apnea (OSA) is thought to be due to effects at the hypoglossal motor nucleus (HMN). Clinical efficacy varies with muscarinic-receptor (MR) subtype affinities. We hypothesized that
Sepehr Niakani +3 more
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First record of Inosperma subsphaerosporum (Inocybaceae) in Indonesia
Inosperma (Inocybaceae) was originally described as a subgenus of Inocybe. Some species of Inosperma are considered edible mushrooms, but this genus also includes a few toxic species with high levels of muscarine.
Иван П. Путра +3 more
doaj +1 more source
Toxicity Mechanisms and Potential Uses of Extracted Mushroom Toxins - Amatoxin, Antamanide, Muscurine [PDF]
Mushroom, as a popular kind of wild edible fungi, has raised the attention of many scientists around the globe, due to the fact that increasing numbers of fatal mushroom poisoning cases worldwide have been reported each year.
Liang Xiaochen, Wang Tianxu
doaj +1 more source
The Constitution of Pseudo-Muscarine (“Synthetic Muscarine”) [PDF]
n ...
openaire +2 more sources
The cholinergic system plays an essential role in central respiratory control, but the underlying mechanisms remain elusive. We used whole-cell recordings in brainstem slices from juvenile mice expressing enhanced green fluorescent protein (EGFP) under ...
Fang Zheng +5 more
doaj +1 more source
Cigarette Smoke Disturbs the Survival of CD8+ Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease. [PDF]
CD8+ T cells (Cytotoxic T cells, Tc) are known to play a critical role in the pathogenesis of smoking related airway inflammation including chronic obstructive pulmonary disease (COPD). However, how cigarette smoke directly impacts systematic CD8+ T cell
Gang Chen +7 more
doaj +1 more source

