Occurrence of muscarinic acetylcholine receptors in wild type and cholinergic mutants of Caenorhabditis elegans [PDF]
JG Culotti, WL Klein
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Endothelial TRPV4–Cx43 signalling complex regulates vasomotor tone in resistance arteries
Abstract figure legend In this study, we investigate, for the first time, the role of endothelial Cx43 hemichannels (hCx43) in the regulation of vasomotor tone. We discovered that TRPV4 channels and Cx43 are in proximity within the endothelium of mouse arterioles.
Pía C. Burboa+7 more
wiley +1 more source
Acetylcholine acts on m2‐muscarinic receptors to excite rat locus coeruleus neurones [PDF]
Terrance M. Egan, R. Alan North
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Chemogenetic Control of Striatal Astrocytes Improves Parkinsonian Motor Deficits in Mice
Main Points Dopamine depletion reduces locomotion‐induced calcium activity in dorsal striatal astrocytes. Chemogenetic activation facilitates astrocyte locomotion responses and improves motor behavior in dopamine lesioned animals. ABSTRACT Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal inputs, which causes ...
Wesley R. Evans+7 more
wiley +1 more source
The study of serum muscarinic acetylcholine receptor subtype 3 (m3AChR)-Specific autoantibodies level in rheumatoid arthritis patients with secondary sjogren syndrome. [PDF]
Fakher HE+3 more
europepmc +1 more source
PRESYNAPTIC MUSCARINIC RECEPTORS INHIBITING ACTIVE ACETYLCHOLINE RELEASE IN THE BULLFROG SYMPATHETIC GANGLION [PDF]
K. Koketsu, Masanobu Yamada
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European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management
ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non‐gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well‐structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut‐brain interaction ...
Carolina Malagelada+34 more
wiley +1 more source
.: In small cell lung carcinoma (SCLC), acetylcholine (ACh) is synthesized and secreted, and it acts as an autocrine growth factor through activation of its receptors, muscarinic receptor (mAChR) and nicotinic receptor (nAChR). Alteration of tumor growth
Nozomi Ami+5 more
doaj
Muscarinic Acetylcholine Receptor M3 Expression and Survival in Human Colorectal Carcinoma-An Unexpected Correlation to Guide Future Treatment? [PDF]
Lobbes LA+7 more
europepmc +1 more source
Abstract Background and Purpose Inflammatory bowel disease (IBD) patients display genetic polymorphisms in toll‐like receptor 4 (TLR4) genes, contributing to dysregulate enteric nervous system (ENS) circuits with increased levels of 5‐HT and alteration of the neuroimmune crosstalk.
Sofia Faggin+12 more
wiley +1 more source