Results 141 to 150 of about 124,416 (341)
Journal of Neuroscience, 2010 Cholinergic neuromodulation of hippocampal circuitry promotes network oscillations and facilitates learning and memory through cellular actions on both excitatory and inhibitory circuits.
Christian A. Cea‐del Rio +5 more
semanticscholar +1 more source
The first 25 years of the Northwestern University SuperAging Program
Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.Abstract During late life, “average” does not mean “intact.” For example, cross‐sectional data from a common word list learning test show that average delayed word recall raw score at age 80 (5/15) is approximately half that at age 56 to 66 (9/15). Cognitive and neurobiological dissolution is therefore implicitly incorporated into concepts of the aging
Sandra Weintraub +3 more
wiley +1 more source
Journal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 2, Page 442-471, August 2025.Abstract Objectives Abdominal pain related disorders of gut–brain interaction (AP‐DGBIs) such as irritable bowel syndrome (IBS) and functional abdominal pain‐not otherwise specified (FAP) are common conditions in children, significantly impacting quality of life.
Jip Groen +17 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.Gastrin‐releasing peptide concentration‐dependently potentiates the cholinergic contractions of mouse gastric fundus circular muscle evoked by electric field stimulation. ABSTRACT Gastrin‐releasing peptide (GRP) and neuromedin B (NMB) are found in the stomach's myenteric plexus and muscular layers.
Diego Currò +2 more
wiley +1 more source
Acetylcholine acts on m2‐muscarinic receptors to excite rat locus coeruleus neurones [PDF]
, 1985 Terrance M. Egan, R. Alan North
openalex +1 more source
British Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2142-2150, August 2025.Abstract Over recent years, studies have shown that science and health profession graduates demonstrate gaps in their fundamental pharmacology knowledge and ability to apply pharmacology concepts in practice. This article reviews the current challenges faced by pharmacology educators, including the exponential growth in discipline knowledge and ...
Clare Guilding +12 more
wiley +1 more source
Coronary Microvascular Dysfunction in Ischaemic Heart Disease: Lessons From Large Animal Models
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.ABSTRACT The coronary microvasculature is principally responsible for matching coronary blood flow to myocardial demand of oxygen and nutrients. Short‐term control of coronary blood flow is achieved via alterations in coronary microvascular tone, whereas long‐term control of coronary flow also involves remodelling of the coronary microvasculature ...
Oana Sorop +3 more
wiley +1 more source
Allosteric interactions at the M3 muscarinic acetylcholine receptor
, 2023 The extracellular loops of muscarinic acetylcholine receptors are predicted to play a role in the binding and regulation of allosteric modulators. Furthermore, the sequence of the five subtypes of muscarinic receptors shows a large degree of diversity in this region.
openaire +4 more sources
Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi
British Journal of Pharmacology, Volume 182, Issue 15, Page 3669-3687, August 2025.Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia +14 more
wiley +1 more source
Digital Chinese Medicine, 2018 : Objective To predict the main active ingredients, potential targets and molecular mechanisms of Yuan Zhi powder in treatment of dementia by using network pharmacology.Methods A database of chemical constituents of Yuan Zhi powder was constructed by ...
Wei-Jie Qiang +11 more
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