Results 161 to 170 of about 124,416 (341)

Inside‐Out IP3‐Mediated G Protein‐Coupled Receptor Activation Drives Intercellular Ca2+ Signaling in the Vascular Endothelium

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
During endothelial cell Ca2+ wave propagation, IP3 in the initiating cell activates IP3Rs on the endoplasmic reticulum, releasing Ca2+ into the cytoplasm. We show that IP3 is required for signal propagation to neighboring cells and propose that this is due to activation of membrane‐bound pore‐dead IP3Rs, as part of a noncanonical signaling inside‐out ...
C. Buckley, X. Zhang, M. D. Lee, C. Wilson, J. G. McCarron   +4 more
wiley   +1 more source

Mechanism of acetylcholine release: possible involvement of presynaptic muscarinic receptors in regulation of acetylcholine release and protein phosphorylation.

, 1979
D. M. Michaelson, Sofia Avissar, Yoel Kloog, Mordechai Sokolovsky   +3 more
openalex   +1 more source

Immunologic mimicry by a monoclonal antibody of the tricyclic anti-depressants' binding site on muscarinic acetylcholine receptors. [PDF]

, 1987
Stéfano Marullo, Johan Hoebeke, J G Guillet, Carl André, A. Donny Strosberg   +4 more
openalex   +1 more source

P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]

, 1998
The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Barnard, EA, Brown, DA, Filippov, AK, Webb, TE   +3 more
core  

Properties of muscarinic acetylcholine receptors in heart cell cultures

, 1978
Jonas Galper, Thomas W. Smith
openalex   +1 more source

Purification of the muscarinic acetylcholine receptor from porcine atria [PDF]

, 1984

openalex   +1 more source

Muscarinic acetylcholine receptors in developing chick heart

, 1977
Jonas Galper, William L. Klein, William A. Catterall   +2 more
openalex   +1 more source

The Forefront for Novel Therapeutic Agents Based on the Pathophysiology of Lower Urinary Tract Dysfunction: Pathophysiology and Pharmacotherapy of Overactive Bladder

Journal of Pharmacological Sciences, 2010
Overactive bladder (OAB) syndrome, which is characterized by a complex of storage symptoms (urinary urgency, frequency, nocturia, and urgency incontinence) is highly prevalent within the general population, causing major distress to patients in terms of ...
Masaki Yoshida, Koichi Masunaga, Takashi Nagata, Makoto Yono, Yukio Homma   +4 more
doaj  

A Role for the Kolliker-Fuse Nucleus in Cholinergic Modulation of Breathing at Night During Wakefulness and NREM Sleep [PDF]

, 2010
For many years, acetylcholine has been known to contribute to the control of breathing and sleep. To probe further the contributions of cholinergic rostral pontine systems in control of breathing, we designed this study to test the hypothesis that ...
Bonis, Joshua M., Forster, Hubert V., Kiner, T., Krause, Katie L., Marshall, B. D., Neumueller, Suzanne E., Pan, Lawrence, Qian, B., Smith, A.   +8 more
core   +1 more source

Current optimization of combined therapy for chronic obstructive pulmonary disease

Терапевтический архив, 2015
Testing the new combined bronchodilator Anoro Ellipta in different clinical trials gives proof to its high clinical efficacy and safety in chronic obstructive pulmonary disease.
E N Popova
doaj