Results 11 to 20 of about 29,139 (279)
Food Science &Nutrition, Volume 11, Issue 1, Page 168-180, January 2023., 2023 The hydro‐ethanolic extract of P. granatum peel was standardized. ;The extract increased superoxide dismutase activity and thiol content, while reduced function of AchE and peroxidation of lipid in the scopolamine‐injured rat’s brain. ;P. granatum may attenuate scopolamine injury through targeting nuclear factor‐E2‐related factor 2 pathway ; Abstract ...
Mahsan Akbarian +5 more
wiley +1 more source
A review of frequently used Kampo prescriptions part 1. Daikenchuto
Traditional &Kampo Medicine, Volume 9, Issue 3, Page 151-179, December 2022., 2022 Abstract Background The original formula name for daikenchuto (DKT) was written in ‘Jin Gui Yao Lue (Kinkiyōryaku in Japanese)’. DKT as used in Japan consists of four types of crude drug. Key findings Although there are few examples of its use in Chinese classical records, it has begun to be used extensively in modern Japan for intestinal obstruction ...
Takao Namiki +5 more
wiley +1 more source
Understanding and treating ejaculatory dysfunction in men with diabetes mellitus
Andrology, Volume 11, Issue 2, Page 379-398, February 2023., 2023 Abstract Diabetes mellitus is a rapidly rising metabolic disorder with important systemic complications. Global figures have demonstrated the prevalence of diabetes mellitus has almost quadrupled from 108 million in 1980 to 422 million in 2014, with a current prevalence of over 525 million.
Ankit Desai +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Localization of muscarinic acetylcholine receptor 2 to the intestinal crypt stem cell compartment
Data in Brief, 2017 The data presented in this article are related to the research article entitled “Distribution of muscarinic acetylcholine receptor subtypes in the murine small intestine” (E.D. Muise, N. Gandotra, J.J. Tackett, M.C. Bamdad, R.A. Cowles, 2016) [1].
Eleanor D. Muise +4 more
doaj +1 more source
Muscarinic Acetylcholine Receptors in the Retina—Therapeutic Implications [PDF]
International Journal of Molecular Sciences, 2021 Muscarinic acetylcholine receptors (mAChRs) belong to the superfamily of G-protein-coupled receptors (GPCRs). The family of mAChRs is composed of five subtypes, M1, M2, M3, M4 and M5, which have distinct expression patterns and functions. In the eye and its adnexa, mAChRs are widely expressed and exert multiple functions, such as modulation of tear ...
Yue Ruan +3 more
openaire +4 more sources
Muscarinic receptor signaling in the pathophysiology of asthma and COPD
Respiratory Research, 2006 Anticholinergics are widely used for the treatment of COPD, and to a lesser extent for asthma. Primarily used as bronchodilators, they reverse the action of vagally derived acetylcholine on airway smooth muscle contraction.
Zaagsma Johan +3 more
doaj +1 more source
Identification, expression and functional characterization of M4L, a muscarinic acetylcholine M4 receptor splice variant. [PDF]
PLoS ONE, 2017 Rodent genomic alignment sequences support a 2-exon model for muscarinic M4 receptor. Using this model a novel N-terminal extension was discovered in the human muscarinic acetylcholine M4 receptor. An open reading frame was discovered in the human, mouse
Douglas A Schober +4 more
doaj +1 more source
Spontaneous Lipid Binding to the Nicotinic Acetylcholine Receptor in a Native Membrane [PDF]
, 2021 The nicotinic acetylcholine receptor (nAChR) and other pentameric ligand-gated ion channels (pLGICs) are native to neuronal membranes with an unusual lipid composition. While it is well-established that these receptors can be significantly modulated by lipids, the underlying mechanisms have been primarily studied in model membranes with only a few ...
arxiv +1 more source
Journal of Ayurveda, 2023 Introduction: Mandukaparni, being one of the medhya rasayanas, has shown remarkable therapeutic effects in the management of psychological disorders. Network pharmacology is the latest scientific collaboration where new drug actions can be established ...
T Adarsh, Giridhar Vedantam
doaj +1 more source