Results 111 to 120 of about 11,132 (239)

Identification of Orthosteric and Allosteric Site Mutations in M2 Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias [PDF]

, 2010
Karen J. Gregory, Nathan E. Hall, Andrew B. Tobin, Patrick M. Sexton, Arthur Christopoulos   +4 more
openalex   +1 more source

Acetylcholine regulates the melanogenesis of retinal pigment epithelia cells via a cAMP-dependent pathway: A non-neuronal function of cholinergic system in retina

Heliyon
The turnover rate of melanogenesis in retinal pigment epithelium (RPE) and its molecular signaling remain unclear. This study aimed to investigate the role of cholinergic signaling in the process of melanogenesis of cultured RPE cells.
Ivan Kong, Gary Ka-Wing Yuen, Qi-Yun Wu, Maggie Sui-Sui Guo, Jin Gao, Tina Ting-Xia Dong, Karl Wah-Keung Tsim   +6 more
doaj  

Modular horizontal network within mouse primary visual cortex

Frontiers in Neuroanatomy
Interactions between feedback connections from higher cortical areas and local horizontal connections within primary visual cortex (V1) were shown to play a role in contextual processing in different behavioral states.
Andreas Burkhalter, Weiqing Ji, Andrew M. Meier, Andrew M. Meier, Rinaldo D. D’Souza   +4 more
doaj   +1 more source

Internalization and Down-regulation of Human Muscarinic Acetylcholine Receptor m2 Subtypes [PDF]

, 1998
Hirofumi Tsuga, Kimihiko Kameyama, Tatsuya Haga, Takeshi Honma, Jelveh Lameh, Wolfgang Sadée   +5 more
openalex   +1 more source

Predicting novel pharmacological activities of compounds using PubChem IDs and machine learning (CID-SID ML model) [PDF]

arXiv
Significance and Object: The proposed methodology aims to provide time- and cost-effective approach for the early stage in drug discovery. The machine learning models developed in this study used only the identification numbers provided by PubChem.
arxiv  

Desensitization and Sequestration of Human m2 Muscarinic Acetylcholine Receptors by Autoantibodies from Patients with Chagas' Disease [PDF]

, 1997
Claudia Pérez Leirós, Leonor Sterin‐Borda, Enri Borda, Juan Carlos Goin, M. Marlene Hosey   +4 more
openalex   +1 more source

Biphasic, Opposing Modulation of Cloned Neuronal α1E Ca Channels by Distinct Signaling Pathways Coupled to M2 Muscarinic Acetylcholine Receptors [PDF]

, 1999
Ulises Meza, Roger A. Bannister, Karim Melliti, Brett Adams   +3 more
openalex   +1 more source

Multiple Topological Domains Mediate Subtype-specific Internalization of the M2 Muscarinic Acetylcholine Receptor

, 2000
Michael L. Schlador, Robert D. Grubbs, Neil M. Nathanson   +2 more
openalex   +1 more source

Arrestin Binding to the M2 Muscarinic Acetylcholine Receptor Is Precluded by an Inhibitory Element in the Third Intracellular Loop of the Receptor [PDF]

, 2000
Katharine B. Lee, J Ptasienski, Robin Pals‐Rylaarsdam, Vsevolod V. Gurevich, Marie Thérèse Hosey   +4 more
openalex   +1 more source

Erratum to “Nature of the oligomers formed by muscarinic m2 acetylcholine receptors in Sf9 cells” [Eur. J. Pharmacol. 421 (2001) 11–22]

, 2001
Paul Park, Chi Shing Sum, David R. Hampson, Hubert H.M. Van Tol, James W. Wells   +4 more
openalex   +1 more source