Results 91 to 100 of about 6,851 (178)

Exploring the Antidiarrheal Properties of Papaya Leaf: Insights In Vivo Study in Mice-Model and In Silico Analysis at M3 Muscarinic Acetylcholine Receptor Interaction

Scientifica
Diarrhea caused by gut motility involves 5-HT3 serotonin receptor (5-HT3R) antagonist, M3 muscarinic acetylcholine receptor (M3-AchR), and H1 histamine receptor (H1R) via their respective agonist.
Nyi Mekar Saptarini, Faruk Jayanto Kelutur, Mary Jho-Anne Tolentino Corpuz   +2 more
doaj   +1 more source

Anti-M3 muscarinic acetylcholine receptor antibodies in systemic lupus erythematosus

, 2015
Fil: Pisoni, Cecilia.
Reina, Silvia Lorena, Pisoni, Cecilia, Eimon, Alicia, Carrizo, Carolina, Arana, Roberto, Borda, Enri Santiago   +5 more
openaire   +2 more sources

Regulation of Src family kinases by muscarinic acetylcholine receptors in heterologous cells and neurons

Frontiers in Molecular Neuroscience
Five muscarinic acetylcholine (mACh) receptor subtypes are divided into two classes: the M1 class (M1, M3, and M5) and the M2 class (M2 and M4). The former is coupled to Gq proteins, while the latter is coupled to Gi/o proteins.
Li-Min Mao, Lexi Young, Xiang-Ping Chu, John Q. Wang, John Q. Wang   +4 more
doaj   +1 more source

Mogrol stimulates G-protein-coupled bile acid receptor 1 (GPBAR1/TGR5) and insulin secretion from pancreatic β-cells and alleviates hyperglycemia in mice

Scientific Reports
Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the triterpenoid ...
Chisato Tanaka, Naoki Harada, Yoshiaki Teraoka, Hiroki Urushizaki, Yoh Shinmori, Teruaki Onishi, Yusuke Yotsumoto, Yuta Ito, Tomoya Kitakaze, Takashi Inui, Yuji Murata, Hiroshi Inui, Ryoichi Yamaji   +12 more
doaj   +1 more source

Understanding the Muscarinic Acetylcholine M3 Receptor: Structure, Function, and Therapeutic Implications

International Journal of Biomedical Science
Muscarinic acetylcholine M receptors (mAChRs) belong to the G protein-coupled receptor (GPCR) superfamily and play a crucial role in regulating and controlling the release of acetylcholine (ACh). This review aims to focus on M3 receptor (M3R) subtype distribution, function, efficacy, and clinical applications.
Shi-wan-er Chen, Jie Wu
openaire   +1 more source

Muscarinic acetylcholine receptor M3 (CHRM3; HM3) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Random Mutagenesis of the M3 Muscarinic Acetylcholine Receptor Expressed in Yeast [PDF]

Journal of Biological Chemistry, 2003
Clarice Schmidt, Bo Li, Lanh Bloodworth, Isolde Erlenbach, Fu-Yue Zeng, Jürgen Wess   +5 more
openaire   +1 more source

Muscarinic acetylcholine receptor M3 (CHRM3; HM3) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Random Mutagenesis of the M3 Muscarinic Acetylcholine Receptor Expressed in Yeast [PDF]

Journal of Biological Chemistry, 2005
Bo Li, Nicola M. Nowak, Soo-Kyung Kim, Kenneth A. Jacobson, Ali Bagheri, Clarice Schmidt, Jürgen Wess   +6 more
openaire   +1 more source

Investigation of Muscarinic Acetylcholine Receptor M₃ Activation in Atomistic Detail: A Chemist's Viewpoint. [PDF]

ChemMedChem
Drabek M, Emmerich R, Djulic N, Bünemann M, Schlitzer M, Kolb P.   +5 more
europepmc   +1 more source