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Upregulation of mRNA Encoding the M5 Muscarinic Acetylcholine Receptor in Human T- and B-Lymphocytes During Immunological Responses

Neurochemical Research, 2003
Lymphocytes possess an independent, non-neuronal cholinergic system. Moreover, both T- and B-lymphocytes express multiple muscarinic acetylcholine receptors (mAChR). To obtain a better understanding of the regulatory mechanisms governing mAChR gene expression in the lymphocytic cholinergic system, we examined the effects of lymphocyte activation on ...
Takeshi, Fujii   +3 more
openaire   +2 more sources

Ligand binding properties of muscarinic acetylcholine receptor subtypes (m1-m5) expressed in baculovirus-infected insect cells.

The Journal of Pharmacology and Experimental Therapeutics, 1995
Five subtypes of muscarinic acetylcholine receptors (m1-m5) have been expressed in insect cells (Spodoptera frugiperda, Sf9) using the baculovirus system. Up to 6 nmol of muscarinic acetylcholine receptors were produced by 1 liter culture; 0.3 to 0.6 (human m1), 3 to 6 (human m2), 2 to 4 (rat m3), 1 to 2 (rat m4) and 0.5 to 1 (human m5) nmol ...
G Z, Dong   +3 more
openaire   +2 more sources

Extrasynaptic acetylcholine signaling through a muscarinic receptor regulates cell migration

Proceedings of the National Academy of Sciences of the United States of America, 2021
Irina Kolotuev   +2 more
exaly  

Identification of a Novel Allosteric Site at the M5Muscarinic Acetylcholine Receptor

ACS Chemical Neuroscience, 2021
Patrick Sexton   +2 more
exaly  

COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5

2021
LINDSLEY CRAIG W   +10 more
openaire   +2 more sources

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