Results 131 to 140 of about 5,023 (210)

Discovery of Pre-Clinical Candidate <b>VU6008055</b>/<b>AF98943</b>: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M₄ Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy. [PDF]

ACS Chem Neurosci
Engers JL, Bollinger SR, Gregro AR, Capstick RA, Spearing PK, Long MF, Tarr JC, Watson KJ, Chang S, Luscombe VB, Rodriguez AL, Cho HP, Qi A, Niswender CM, Bubser M, Gould RW, Robb WH, Byun N, Gore J, Jones CK, Thomsen MS, Bridges TM, Boutaud O, Conn PJ, Engers DW, Lindsley CW, Temple KJ.   +26 more
europepmc   +1 more source

Long-term muscarinic inhibition increases intrinsic excitability through the upregulation of A-type potassium currents in cortical neurons. [PDF]

Front Cell Dev Biol
Riquelme D, Romo-Toledo P, Leyton P, Moreno C, Leiva-Salcedo E.   +4 more
europepmc   +1 more source

A Brief Overview of Cholinergic and Phosphodiesterase-5 Inhibitors in Diabetic Bladder Dysfunction. [PDF]

Int J Mol Sci
Kallinikas G, Haronis G, Kallinika E, Kozyrakis D, Rodinos E, Filios A, Filios P, Mityliniou D, Safioleas K, Zarkadas A, Bozios D, Karmogiannis A, Konstantinopoulos V, Konomi AM, Ektesabi AM, Tsoporis JN.   +15 more
europepmc   +1 more source

Muscarinic Modulation of Network Excitability and Short-Term Dynamics in the Dorsal and Ventral Hippocampus. [PDF]

MicroPubl Biol
Tsotsokou G, Fassea M, Papatheodoropoulos C.   +2 more
europepmc   +1 more source

Muscarinic Receptors in Cardioprotection and Vascular Tone Regulation. [PDF]

Physiol Res
Dolejší E, Janoušková A, Jakubík J.
europepmc   +1 more source

Weight Gain With Advancing Age Is Controlled by the Muscarinic Acetylcholine Receptor M4 in Male Mice.

Endocrinology
Takahashi T, Takase Y, Shiraishi A, Matsubara S, Watanabe T, Kirimoto S, Yamagaki T, Osawa M.   +7 more
europepmc   +1 more source

[¹¹C]MK-6884 PET imaging reveals lower M₄ muscarinic acetylcholine receptor availability following cocaine self-administration in male rats. [PDF]

Pharmacol Rep
Gollapelli KK, Krizan I, Bhoopal B, Damuka N, Moriarty C, Miller M, Sai KKS, Gould RW.   +7 more
europepmc   +1 more source

Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse [PDF]

, 2006
Akinci, Sibel, Haberberger, Rainer Viktor, Koepsell, Hermann, Kummer, Wolfgang, Lips, Katrin S, Schinkel, Alfred H, Wess, Jurgen, Wessler, Ignatz, Wiegand, Silke   +8 more
core  

The Role of Muscarinic Acetylcholine Receptor M₃ in Cardiovascular Diseases. [PDF]

Int J Mol Sci
Liu X, Yu Y, Zhang H, Zhang M, Liu Y.
europepmc   +1 more source

Epitomic profiling and functional characteristics of pemphigus vulgaris autoantibody binding to keratinocyte M3 muscarinic acetylcholine receptor. [PDF]

J Biol Chem
Reyes-Ruiz JM, Chernyavsky A, Grando SA, Glabe C.   +3 more
europepmc   +1 more source