Results 71 to 80 of about 20,015 (223)

Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection

open access: yesPharmacological Research
Δ9-tetrahydrocannabinol (THC), the chief psychoactive ingredient of cannabis, acts in the brain primarily via cannabinoid CB1 receptors. These receptors are implicated in several forms of synaptic plasticity – depolarization-induced suppression of ...
Michaela Dvorakova   +2 more
doaj   +1 more source

ATP and Odor Mixture Activate TRPM5-Expressing Microvillous Cells and Potentially Induce Acetylcholine Release to Enhance Supporting Cell Endocytosis in Mouse Main Olfactory Epithelium

open access: yesFrontiers in Cellular Neuroscience, 2018
The main olfactory epithelium (MOE) functions to detect odor molecules, provide an epithelial surface barrier, and remove xenobiotics from inhaled air.
Ziying Fu   +3 more
doaj   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

open access: yes, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse [PDF]

open access: yes, 2006
Background It has been proposed that serotonin (5-HT)-mediated constriction of the murine trachea is largely dependent on acetylcholine (ACh) released from the epithelium.
Akinci, Sibel   +8 more
core   +3 more sources

Gene expression of muscarinic, tachykinin and purinergic receptors in porcine bladder: comparison with cultured cells

open access: yesFrontiers in Pharmacology, 2013
Urothelial cells, myofibroblasts, and smooth muscle cells are important cell types contributing to bladder function. Multiple receptors including muscarinic (M3/M5), tachykinin (NK1/NK2) and purinergic (P2X1/P2Y6) receptors are involved in bladder motor ...
Forough eBahadory   +3 more
doaj   +1 more source

Expression and function of G-protein-coupled receptorsin the male reproductive tract [PDF]

open access: yes, 2009
This review focuses on the expression and function of muscarinic acetylcholine receptors (mAChRs), α1-adrenoceptors and relaxin receptors in the male reproductive tract.
ABOUD R   +267 more
core   +3 more sources

Nuclear calcium signaling evoked by cholinergic stimulation in hippocampal CA1 pyramidal neurons [PDF]

open access: yes, 2002
The cholinergic system is thought to play an important role in hippocampal-dependent learning and memory. However, the mechanism of action of the cholinergic system in these actions in not well understood.
Power, JM, Sah, P
core   +2 more sources

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Accumbal Cholinergic Interneurons Differentially Influence Motivation Related to Satiety Signaling [PDF]

open access: yes, 2017
Satiety, rather than all or none, can instead be viewed as a cumulative decrease in the drive to eat that develops over the course of a meal. The nucleus accumbens (NAc) is known to play a critical role in this type of value reappraisal, but the ...
Aitta-aho, Teemu Heikki Juhani   +8 more
core   +2 more sources

Modulation of c-Jun NH2-Terminal (JNK) by Cholinergic Autoantibodies from Patients with Sjögren’s Syndrome [PDF]

open access: yes, 2011
Background: We wanted to determine (via an immunopharmacological approach) whether the c-Jun NH2 terminal kinase (JNK) cascade is phosphorylated in the submandibular gland by carbachol and cholinergic autoantibodies (IgG) present in the sera of patients ...
Borda, Enri Santiago   +3 more
core   +1 more source

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