Results 71 to 80 of about 1,293,750 (146)

Muscarinic M2 acetylcholine receptor distribution in the guinea-pig gastrointestinal tract [PDF]

open access: yes, 2006
In the enteric nervous system, acetylcholine is the most common neurotransmitter to induce gastrointestinal smooth muscle contractions. Cholinergic signaling is mediated by muscarinic acetylcholine receptors on the surface of smooth muscle cells.
NOJYO, Yoshiaki, IINO, Satoshi
core   +1 more source

Muscarinic acetylcholine receptor M5 is involved in spermatogenesis through the modification of cell-cell junctions. [PDF]

open access: yesReproduction, 2021
Han X   +9 more
europepmc   +1 more source

The m5 muscarinic receptor: Labeling and localization studies

open access: yes, 1997
The aims of this study were: (1) to develop binding conditions that labeled predominantly the m5 muscarinic receptor subtype; (2) to use m5-selective labeling conditions to study the distribution of the m5 receptor subtype in the rat brain and make ...
Reever, Carolyn
core   +3 more sources

Non-Neuronal Functions of the M2 Muscarinic Acetylcholine Receptor [PDF]

open access: yes, 2013
Acetylcholine is an important neurotransmitter whose effects are mediated by two classes of receptors. The nicotinic acetylcholine receptors are ion channels, whereas the muscarinic receptors belong to the large family of G protein coupled seven ...
Kühne, Sina   +9 more
core   +1 more source

The actions of Pasteurella multocida toxin on neuronal cells [PDF]

open access: yes, 2014
Pasteurella multocida toxin (PMT) activates the G-proteins Gα, Gα, Gα Gα and Gα by deamidation of specific glutamine residues. A number of these alpha subunits have signalling roles in neurones.
Lax, Alistair; id_orcid   +13 more
core   +1 more source

a bile acid/acetylcholine hybrid, is a muscarinic receptor antagonist

open access: yes, 2020
Previous work from our laboratory indicates that bile acids, specifically lithocholic acid conjugates, interact with muscarinic receptors on gastric chief cells.
Kunrong Cheng   +5 more
core  

Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors [PDF]

open access: yes, 2002
GABA(A) receptors are the principal sites of fast synaptic inhibition in the brain. These receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta, and pi, but the ...
Trevor G Smart   +7 more
core  

RT-PCR reveals muscarinic acetylcholine receptor mRNA in the pre-Bötzinger complex

open access: yes, 2001
Muscarinic receptors mediate the postsynaptic excitatory effects of acetylcholine (ACh) on inspiratory neurons in the pre-Bötzinger complex (pre-BötC), the hypothesized site for respiratory rhythm generation.
Cindy H. Huang   +5 more
core   +1 more source

Morphine-induced Locomotion Increases following Viral Transfection of M5 Muscarinic Receptor Genes in the Ventromedial Hypothalamus of Wild-type Mice [PDF]

open access: yes, 2011
Excitatory M5 muscarinic acetylcholine receptors are expressed at the highest level in the brain, in the ventromedial hypothalamus (VMH). M5 knockout (KO) mice emit fewer ultrasonic vocalizations (USVs) during mating, and show 40-50% lesser morphine ...
Nawaz, Sabrina
core   +2 more sources

M1 muscarinic acetylcholine receptor in Alzheimer's disease

open access: yes, 2014
The degeneration of cholinergic neurons and cholinergic hypofunction are pathologies associated with Alzheimer's disease (AD). Muscarinic acetylcholine receptors (mAChRs) mediate acetylcholine-induced neurotransmission and five mAChR subtypes (M1-M5 ...
Li, Yanfang   +6 more
core   +1 more source

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