Neurogastroenterology &Motility, EarlyView.Amyloidosis in the central and enteric nervous system contributes to cognitive deficits and gastrointestinal dysmotility—the constipation in Alzheimer's disease (AD). APP/PS1 mice, a transgenic mouse model of amyloidosis, recapitulated the amyloidosis in the central nervous system; they were unsustainable in recapitulating the amyloidosis in the ...
Roxanne Fernandes +8 more
wiley +1 more source
Oral Adverse Effects of Antipsychotic Medications: A Case/Noncase Analysis of EudraVigilance Data
Oral Diseases, EarlyView.ABSTRACT Objective Neuropsychiatric disorders are associated with poor oral health, with antipsychotics as potential contributors. This study aimed to analyse the oral adverse effects of antipsychotics using the EudraVigilance database. Methods A case/noncase analysis was conducted to calculate reporting odds ratios (ROR) and assess the ...
Leire Urien +5 more
wiley +1 more source
Neuroimmune pathophysiology of long COVID
Psychiatry and Clinical Neurosciences, EarlyView.Although COVID‐19 was originally considered a respiratory illness, it is now well established that SARS‐CoV‐2 infection can have far‐reaching impacts on the nervous system. Neurological symptoms such as chemosensory dysfunction are frequently observed during acute infection and approximately 10% of COVID‐19 cases will go on to develop new or persistent
Janna K. Moen +2 more
wiley +1 more source
P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]
, 1998 The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Barnard, EA +3 more
core
Axonal transport of muscarinic cholinergic receptors in rat vagus nerve: high and low affinity agonist receptors move in opposite directions and differ in nucleotide sensitivity [PDF]
, 1982 MA Zarbin, JK Wamsley, MJ Kuhar
openalex +1 more source
Mapping Bullous Emphysema With Lung Ultrasound: A Prospective Multicentre Study
Respirology, EarlyView.ABSTRACT Background and Objectives Lung ultrasound holds high diagnostic performance for pleural diseases, notably pneumothorax. Bullous emphysema is a potential differential diagnosis of pneumothorax on ultrasound, but its precise semiology is poorly known.
Kinan El Husseini +8 more
wiley +1 more source
Bile acids differentially regulate longitudinal smooth muscle contractility in everted mouse ileum
FASEB BioAdvancesBile acids regulate gastrointestinal motility by mechanisms that are poorly understood. Standard isolated tissue bath assays might not recapitulate in vivo physiology if contractile responses to certain bile acids require direct application to the ...
Peace N. Dike +3 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad +5 more
wiley +1 more source
International Journal of COPD, 2014 Mario Malerba,1 Jaymin Bhagwanji Morjaria,2 Alessandro Radaeli3 1Department of Internal Medicine, University of Brescia, Brescia, Italy; 2Department of Academic Respiratory Medicine, Hull York Medical School, University of Hull, Castle Hill Hospital ...
Malerba M, Morjaria JB, Radaeli A
doaj
Quantitative effects of some muscarinic agonists on evoked surface‐negative field potentials recorded from the guinea‐pig olfactory cortex slice [PDF]
, 1988 Stephen H. Williams, Andrew Constanti
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