Results 161 to 170 of about 578,217 (295)

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

open access: yes
The Journal of Physiology, EarlyView.
Richard J. A. Wilson   +1 more
wiley   +1 more source

Risk of diabetes mellitus with olanzapine compared to clozapine: A systematic review and meta‐analysis

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim Olanzapine and clozapine are second‐generation antipsychotics commonly associated with metabolic side effects. In Japan, olanzapine is designated as “principally contraindicated” for patients with diabetes, while clozapine is “used with caution,” despite similar pharmacological profiles.
Keigo Onda   +2 more
wiley   +1 more source

Impact of antipsychotics, antiparkinsonian drugs, and anthraquinone stimulant laxatives on severe constipation in patients with schizophrenia

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
This study investigated risk factors for severe constipation in patients with schizophrenia receiving pharmacological treatment. A retrospective analysis of over 4000 inpatients revealed that high‐dose use of clozapine, haloperidol, antiparkinsonian drugs, and anthraquinone stimulant laxatives significantly increased the risk.
Toshiaki Nadaya   +3 more
wiley   +1 more source

Applying High‐Dimensional Propensity Scores in a Study of Inhaled Corticosteroids and COVID‐19 Outcomes

open access: yesPharmacoepidemiology and Drug Safety, Volume 34, Issue 12, December 2025.
ABSTRACT Background In pharmacoepidemiologic studies of COVID‐19, there were concerns about bias from residual confounding. We investigated the effects of inhaled corticosteroids (ICS) on COVID‐19 outcomes, applying high‐dimensional propensity scores (HDPS) to adjust for unmeasured confounding.
Marleen Bokern   +5 more
wiley   +1 more source

Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
ABSTRACT Inhibition of vasocontraction accounts for side effects in treating voiding symptoms in benign prostatic hyperplasia (BPH). We examined the vasoactivity of compounds previously showing inhibition of prostate smooth muscle contraction. Contractions of porcine renal interlobar and coronary arteries were induced by agonists or electric field ...
Guangyang Liu   +6 more
wiley   +1 more source

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