Results 161 to 170 of about 25,052 (251)
SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW CHIRAL MUSCARINIC ANTAGONISTS
, 1995 The two pairs of enantiomers of isoxazolidin-3-ones 3 and 4 were synthesized by means of Lipase PS-catalyzed hydrolyses of suitable racemic butyrates.
M. De Amici +9 more
core
Selectivity Profile of Some Recent Muscarinic Antagonists in Bovine and Guinea-Pig Trachea and Heart
, 1994 The functional affinities of some recently developed subtype-selective muscarinic antagonists towards bovine tracheal smooth muscle muscarinic M(3) receptors were established and compared to binding affinities for bovine cardiac M(2) and functional ...
Hamstra, J.J. +3 more
core +1 more source
Therapeutics and Clinical Risk Management, 2019 Christine Jenkins Department of Thoracic Medicine, The George Institute for Global Health and Concord Clinical School, University of Sydney, Sydney, NSW, Australia Abstract: Despite the availability of a range of treatment options and management ...
Jenkins C
doaj
Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Natalia Murataeva +3 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.Bitter taste receptors (T2Rs) play an important role in physiological and cellular responses. Bitter tasting chemicals and microbial metabolites can bind to T2R14, which enables interactions between T2R14 and specific intracellular domains of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel.
Tejas Gupte +8 more
wiley +1 more source
Muscarinic acetylcholine receptors : investigation of interactions with agonists and antagonists
, 1981 In the present investigation interactions of agonists and antagonists with the muscarinic acetylcholine receptor from rat cerebral cortex and rat ileum smooth muscle have been characterized.It is suggested that the binding of antagonist involves two ...
Hedlund, Britta,
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International Journal of COPD, 2015 Sanjeevan Muruganandan,1 Lata Jayaram2,3 1Department of Respiratory and Sleep Medicine, Austin Health, 2Department of Respiratory and Sleep Medicine, Western Health, 3University of Melbourne, Melbourne, Victoria, Australia Abstract: Chronic obstructive
Muruganandan S, Jayaram L
doaj
Structure-activity guided design of novel long-acting antagonists of muscarinic receptors
Given the broad range of functions that muscarinic receptors subserve, it is of fundamental importance to find subtype-selective ligands for therapeutic use in specific disorders.
Jan Korabecny
core
Evening administration of long-acting muscarinic antagonists in COPD - a randomized controlled trial. [PDF]
BMC Pulm MedSivapalan P +13 more
europepmc +1 more source
Long-Acting Muscarinic Antagonists for the Treatment of Difficult-to-Treat and Severe Asthma: A Narrative Review Focusing on Inflammation from Bench to Bedside. [PDF]
J Inflamm ResCalzetta L +6 more
europepmc +1 more source