Results 161 to 170 of about 42,993 (314)

Effects of a single long-acting muscarinic antagonist agent and a long-acting muscarinic antagonist/long-acting β2-adrenoceptor agonist combination on lung function and symptoms in untreated COPD patients in Japan

, 2018
Hideyasu Yamada, Norihito Hida, Nobuyuki Hizawa   +2 more
openalex   +2 more sources

Reciprocal molecular and cellular cholinergic working memory impairments in Alzheimer's disease model mice

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION The degeneration of basal forebrain cholinergic neurons is a key pathophysiological feature of Alzheimer's disease (AD). These cholinergic neurons target cortical neurons including those in the granular retrosplenial cortex (RSG) to facilitate essential cognitive functions.
Chloe I. Rybicki‐Kler, Isla A. W. Brooks, Izabela Jedrasiak‐Cape, Tao Deng, Cassandra Avila, Elizabeth Brouns, Alex Lekander, Omar J. Ahmed   +7 more
wiley   +1 more source

Botulinum Toxin (Dysport) to Prevent Radiation‐Induced Dysfunction of Salivary Glands in Head and Neck Cancer

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background The main goal of this pilot trial was to investigate the efficacy of botulinum toxin (Dysport) injection before radiotherapy in preserving salivary gland secretion in patients with head and neck cancer. Methods Sixteen patients with head and neck cancer were enrolled, 9 received 50 IU Dysport, and 7 recieved NaCl (0.9%) into the ...
Farshid Farhan, Iraj Eyvaz‐zadeh, Shayan Forghani, Amirhossein Shahsavand, Reza Samiee, Sepideh Mansouri, Mehrshad Abbasi, Ali Kazemian, Mahdi Aghili, Mehrdad Jafari, Ebrahim Karimi, Ebrahim Esmati, Fatemeh Jafari   +12 more
wiley   +1 more source

Paeoniflorin, a Major Constituent of Peony Root, Reverses Muscarinic M1-Receptor Antagonist-Induced Suppression of Long-Term Potentiation in the Rat Hippocampal Slice.

, 2000
Keiichi Tabata, Kinzo Matsumoto, Hiroshi Watanabe   +2 more
openalex   +1 more source

Vibegron for Anticholinergic‐Resistant Pediatric Neurogenic Lower Urinary Tract Dysfunction After Spinal Cord Amputation: A Case Report

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Pediatric neurogenic lower urinary tract dysfunction (NLUTD) is commonly managed with anticholinergic agents and clean intermittent catheterization (CIC). However, treatment options are limited for patients who remain resistant to conventional therapy, particularly following spinal cord surgery. Case Presentation A 14‐year‐old boy
Kohei Mori, Izuru Shiba, Haruko Miyazawa, Noriaki Samejima, Koga Horiuchi, Hirokazu Ishikawa, Yutaka Shiono, Kazumasa Matsumoto   +7 more
wiley   +1 more source

Barriers to achieving asthma control in adults: evidence for the role of tiotropium in current management strategies

Therapeutics and Clinical Risk Management, 2019
Christine Jenkins Department of Thoracic Medicine, The George Institute for Global Health and Concord Clinical School, University of Sydney, Sydney, NSW, Australia Abstract: Despite the availability of a range of treatment options and management ...
Jenkins C
doaj  

A Potent, Long-Acting, Orally Active (2R)-2-[(1R)-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenylacetamide:  A Novel Muscarinic M₃ Receptor Antagonist with High Selectivity for M₃ over M₂ Receptors

, 2000
Morihiro Mitsuya, Kensuke Kobayashi, Kumiko Kawakami, Atsushi Satoh, Yoshio Ogino, Taro Kakikawa, Norikazu Ohtake, Toshifumi Kimura, Hiroyasu Hirose, Akio Sato, Tomosige Numazawa, Takuro Hasegawa, Kazuhito Noguchi, Toshiaki Mase   +13 more
openalex   +1 more source

Binding and functional profiles of the selective M₁muscarinic receptor antagonists trihexyphenidyl and dicyclomine [PDF]

, 1986
Antonio Giachetti, E. Giraldo, H. Ladinsky, E. Montagna   +3 more
openalex   +1 more source

The pharmacokinetics and safety of vonoprazan in adolescents and children with gastroesophageal reflux disease

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 5, Page 1153-1161, May 2026.
Abstract Objectives Vonoprazan, a potassium‐competitive acid blocker, provides more rapid, potent, and durable elevations in gastric pH than proton pump inhibitors in adults and may be a treatment option for adolescents and children with gastroesophageal reflux disease (GERD).
Darcy J. Mulford, David A. Gremse, Yu‐Ming Chang, Eckhard Leifke, Thomas Wagner, Axel Facius, Galen Witt   +6 more
wiley   +1 more source

The effect of the muscarinic M 1 receptor antagonist biperiden on cognition in medication free subjects with psychosis

, 2017
Claudia Vingerhoets, Geor Bakker, J. Van Dijk, Oswald Bloemen, Ya Wang, Raymond C. K. Chan, Jan Booij, Thérèse van Amelsvoort   +7 more
openalex   +2 more sources