Results 201 to 210 of about 43,320 (312)

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist [PDF]

open access: bronze, 2012
Kazuko Haga   +10 more
openalex   +1 more source

Cluster Analysis to Identify Distinct Asthma Phenotypes in the ATLANTIS Cohort

open access: yesAllergy, Volume 81, Issue 1, Page 185-196, January 2026.
This study identified four clinically distinct asthma clusters. The most severe cluster was characterized by type 2 inflammation and exhibited both large and small airways obstruction, as well as air trapping on CT. Patients in the earlier‐onset cluster exhibited more severe bronchial hyperresponsiveness despite a relatively preserved lung function ...
Pauline J. M. Kuks   +18 more
wiley   +1 more source

Effects of Muscarinic Antagonists on Experimental Nasal Secretion in Guinea Pigs

open access: diamond, 1991
Hiroyuki Mizuno   +5 more
openalex   +1 more source

ADME properties of CHF6366, a novel bi-functional M3 muscarinic receptor antagonist and ß2 adrenoceptor agonist (MABA) radiolabelled at both functional moieties

open access: gold, 2023
Alberto Ghiglieri   +6 more
openalex   +1 more source

State‐dependent regulation of the Kv7.2 channel voltage sensor by QO‐58

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 333-348, January 2026.
Background and Purpose KV7(KCNQ) potassium channels are key modulators of neuronal excitability, and promising targets for development of drugs for epilepsy and pain. We investigated a candidate KV7 drug, QO‐58, which has been previously described but has an unclear mechanism of action.
Richard Kanyo   +3 more
wiley   +1 more source

A Novel Muscarinic Antagonist R2HBJJ Inhibits Non-Small Cell Lung Cancer Cell Growth and Arrests the Cell Cycle in G0/G1

open access: gold, 2012
Nan Hua   +10 more
openalex   +2 more sources

Bronchodilatory effects of aclidinium bromide, a long-acting muscarinic antagonist, in COPD patients [PDF]

open access: bronze, 2009
Guy Joos   +7 more
openalex   +1 more source

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