Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist [PDF]
Kazuko Haga +10 more
openalex +1 more source
Cluster Analysis to Identify Distinct Asthma Phenotypes in the ATLANTIS Cohort
This study identified four clinically distinct asthma clusters. The most severe cluster was characterized by type 2 inflammation and exhibited both large and small airways obstruction, as well as air trapping on CT. Patients in the earlier‐onset cluster exhibited more severe bronchial hyperresponsiveness despite a relatively preserved lung function ...
Pauline J. M. Kuks +18 more
wiley +1 more source
Effects of Muscarinic Antagonists on Experimental Nasal Secretion in Guinea Pigs
Hiroyuki Mizuno +5 more
openalex +1 more source
Patient-Reported Burden of Illness in a Prevalent COPD Population Treated with Long-Acting Muscarinic Antagonist Monotherapy: A Claims-Linked Patient Survey Study [PDF]
Beth Hahn +5 more
openalex +1 more source
Optimal Bronchodilation for COPD Patients: Are All Long-Acting β₂-Agonist/Long-Acting Muscarinic Antagonists the Same? [PDF]
Miravitlles M +3 more
europepmc +1 more source
Comparison of the muscarinic antagonist effects of scopolamine and L-687,306
Gail Winger +2 more
openalex +2 more sources
State‐dependent regulation of the Kv7.2 channel voltage sensor by QO‐58
Background and Purpose KV7(KCNQ) potassium channels are key modulators of neuronal excitability, and promising targets for development of drugs for epilepsy and pain. We investigated a candidate KV7 drug, QO‐58, which has been previously described but has an unclear mechanism of action.
Richard Kanyo +3 more
wiley +1 more source
Bronchodilatory effects of aclidinium bromide, a long-acting muscarinic antagonist, in COPD patients [PDF]
Guy Joos +7 more
openalex +1 more source

