Results 51 to 60 of about 22,691 (214)
Long-Term Efficacy of Mirabegron Add-On Therapy to Antimuscarinic Agents in Patients With Spinal Cord Injury [PDF]
Annals of Rehabilitation Medicine, 2019 Objective To evaluate the long-term efficacy of mirabegron add-on therapy in patients with spinal cord injury (SCI) based on an urodynamic study.
Seok-Hee Han +4 more
doaj +1 more source
The Effect Of A Muscarinic Antagonist On The Lipase Activity
, 2015 Lipases constitute one of the most important groups of industrial enzymes that catalyze the hydrolysis of triacylglycerol to glycerol and fatty acids. Muscarinic antagonist relieves smooth muscle spasm of the gastrointestinal tract and effect on the cardiovascular system.
Zohreh Bayat, Dariush Minai-Tehrani
openaire +1 more source
Effect of Neuromodulation of Short-Term Plasticity on Information Processing in Hippocampal Interneuron Synapses [PDF]
arXiv, 2018 Neurons in a micro-circuit connected by chemical synapses can have their connectivity affected by the prior activity of the cells. The number of synapses available for releasing neurotransmitter can be decreased by repetitive activation through depletion of readily releasable neurotransmitter (NT), or increased through facilitation, where the ...
arxiv
Weakly Coupled Oscillators in a Slowly Varying World [PDF]
, 2016 We extend the theory of weakly coupled oscillators to incorporate slowly varying inputs and parameters. We employ a combination of regular perturbation and an adiabatic approximation to derive equations for the phase-difference between a pair of oscillators. We apply this to the simple Hopf oscillator and then to a biophysical model.
arxiv +1 more source
Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice
Disease Models & Mechanisms, 2013 SUMMARY Myopia is a huge public health problem worldwide, reaching the highest incidence in Asia. Identification of susceptible genes is crucial for understanding the biological basis of myopia.
Veluchamy A. Barathi +7 more
doaj +1 more source
Jurnal Kesehatan, 2020 Imidafenacin is a new antimuscarinic agent in Indonesia that was recently approved in 2019 to treat overactive bladder (OAB) symptoms, including urinary incontinence, urinary frequency, and urinary urgency.
Steven Victoria Halim
doaj +1 more source
Altruism and Antagonistic Pleiotropy in Penna Ageing Model [PDF]
arXiv, 2004 The Penna ageing model is based on mutation accumulation theory. We show that it also allows for self-organization of antagonistic pleiotropy which helps at young age at the expense of old age. This can be interpreted as emergence of altruism.
arxiv
Guidelines for the Treatment of Urinary Incontineence and Overactive Bladder
South African Family Practice, 2002 Urinary incontinence (UI) is the involuntary leakage of urine, while overactive bladder (OAB) is characterised by frequency, nocturia and urgency, with or without incontinence.
C.F. Heyns, G.W. Rienhardt
doaj +1 more source
Journal of Pharmacological Sciences, 2020 Cholinergic neurons play an important role in the higher functions of the brain, such as the memory, cognition, and nociception. However, the exact mechanism behind how the stimulation of all the muscarinic M1 receptors in the entire brain results in the
Keisuke Migita +7 more
doaj
Muscarinic Receptor Antagonists: Effects on Pulmonary Function [PDF]
, 2011 In healthy lungs, muscarinic receptors control smooth muscle tone, mucus secretion, vasodilation, and inflammation. In chronic obstructive pulmonary disease (COPD) and asthma, cholinergic mechanisms contribute to increased bronchoconstriction and mucus secretion that limit airflow.
Allison D. Fryer, Kalmia S. Buels
openaire +3 more sources