Results 21 to 30 of about 56,565 (298)
Journal of Pharmacological Sciences, 2008 Muscarinic receptors in the human and rat lower urinary tract (urinary bladder detrusor muscle and mucosa, and prostate) were identified by intact tissue segment binding assays with two radioligands, and the effects of prolonged receptor activation in ...
Abu Syed Md Anisuzzaman +8 more
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Functional effects of KCNQ K+ channels in airway smooth muscle
Frontiers in Physiology, 2013 KCNQ (Kv7) channels underlie a voltage-gated K+ current best known for control of neuronal excitability, and its inhibition by Gq/11-coupled, muscarinic signaling. Studies have indicated expression of KCNQ channels in airway smooth muscle (ASM), a tissue
Alexey I Evseev +7 more
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Delineating muscarinic receptor functions [PDF]
Proceedings of the National Academy of Sciences, 1999 Acetylcholine, as the first chemical molecule to be established as a neurotransmitter, has attracted enduring interest from researchers over several decades. However, deciphering all of the physiological manifestations associated with actions of this molecule has been difficult, and many mysteries of cholinergic neurotransmission still remain to be ...
Marc G. Caron, Raul R. Gainetdinov
openaire +3 more sources
Vitamin E can compensate the density of M1 receptors in the hippocampus of scopolamine-treated rats
Folia Neuropathologica, 2018 M1 muscarinic receptor plays a fundamental role in memory and is closely associated with Alzheimer’s disease (AD); it has long been assumed as a therapeutic goal. By activating of the cholinergic receptor vitamin E helps with memory retention.
Ali Sayyahi +3 more
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Effects of muscarinic and nicotinic receptors on contextual modulation in macaque area V1
Scientific Reports, 2021 Context affects the salience and visibility of image elements in visual scenes. Collinear flankers can enhance or decrease the perceptual and neuronal sensitivity to flanked stimuli. These effects are mediated through lateral interactions between neurons
Jose L. Herrero, Alexander Thiele
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FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Journal of Pharmacological Sciences, 2007 The inotropic response to muscarinic receptor stimulation of isolated chick ventricular myocardium was examined at various developmental stages, and the receptor subtype involved was pharmacologically characterized.
Hideaki Nouchi +7 more
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Advanced Healthcare Materials, EarlyView.Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati +12 more
wiley +1 more source
Journal of Biomedical Science, 2009 Acetylcholine (ACh), the first neurotransmitter to be identified, regulate the activities of central and peripheral functions through interactions with muscarinic receptors. Changes in muscarinic acetylcholine receptor (mAChR) have been implicated in the
Mathew Jobin +3 more
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Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundThe authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides.MethodsA catheter ...
Cheon-Hee Park +3 more
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