Results 131 to 140 of about 43,735 (227)

In Vivo Evaluation of Psoralen in a Copper Sulfate–Induced Chick (Gallus gallus domesticus) Emesis Model and In Silico Analysis of Its Interaction With D2, 5‐HT3A, and Muscarinic Receptors

ChemistryOpen, Volume 15, Issue 8, August 2026.
Psoralen (PSN) demonstrates significant dose‐dependent antiemetic activity in a copper sulfate–induced chick emesis model. Integrated in vivo and in silico analyses reveal reduced retching frequency, prolonged latency, and favorable multi‐receptor interactions with D2, 5‐HT3A, and muscarinic receptors, highlighting PSN as a promising multi‐target ...
Kishor Chandra, Sharif Uddin Bahar, Khadija Akter, Mst Muslima Khatun, Samiran Sadhukhan, Progna Saha Puja, Fazley Rohan, Md Shimul Bhuia, Mohammed Alfaifi, Faisal H. Altemani, Faisal Alsenani, Salehin Sheikh, Muhammad Torequl Islam   +12 more
wiley   +1 more source

Bile Acids Are Potential Negative Allosteric Modulators of M1 Muscarinic Receptors. [PDF]

Biomolecules
Yu W, MacKerell AD, Weber DJ, Raufman JP.   +3 more
europepmc   +1 more source

Fusion with Promiscuous Gα₁₆ Subunit Reveals Signaling Bias at Muscarinic Receptors. [PDF]

Int J Mol Sci, 2021
Randáková A, Nelic D, Hochmalová M, Zimčík P, Mulenga MJ, Boulos J, Jakubík J.   +6 more
europepmc   +1 more source

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, Volume 36, Issue 8, Page 887-898, August 2026.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa, Debra Faulk, Vinicius Caldeira Quintao, Niekoo Abbasian, Hans D. de Boer, Ricardo Vieira Carlos   +5 more
wiley   +1 more source

Physiological Significance of Endothelial M3 Muscarinic Receptors During Exercise. [PDF]

Circ Res
Ackland GL, Hosford PS, Gutierrez Del Arroyo A, Korsak A, Machhada A, Pickard J, Gomez De La Torre GG, Stuckey DJ, Tinker A, Tobin AB, Jeon J, Wess J, Gourine AV.   +12 more
europepmc   +1 more source

Drug Design Targeting the Muscarinic Receptors and the Implications in Central Nervous System Disorders. [PDF]

Biomedicines, 2022
Johnson CR, Kangas BD, Jutkiewicz EM, Bergman J, Coop A.   +4 more
europepmc   +1 more source

Dissociated Biologic Responses Across the United Airway: A Case Report of Severe Asthma With Chronic Rhinosinusitis With Nasal Polyps and Eosinophilic Otitis Media

Respirology Case Reports, Volume 14, Issue 8, August 2026.
We report a case of severe asthma with chronic rhinosinusitis with nasal polyps and eosinophilic otitis media that was successfully controlled by switching biologic therapy from dupilumab to mepolizumab. Careful monitoring of disease activity and consideration of biologic switching may help achieve optimal control with currently available biologics ...
Tomoko Tajiri, Naoki Takemoto, Toshiya Minakata, Motohiko Suzuki, Yoshiyuki Ozawa, Hirotsugu Ohkubo   +5 more
wiley   +1 more source

Targeting muscarinic receptors in schizophrenia treatment: Novel antipsychotic xanomeline/trospium chloride. [PDF]

World J Psychiatry
Pejčić AV.
europepmc   +1 more source

Breast cancer: Muscarinic receptors as new targets for tumor therapy. [PDF]

World J Clin Oncol, 2021
Español A, Salem A, Sanchez Y, Sales ME.   +3 more
europepmc   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source