Results 181 to 190 of about 52,654 (280)

Breast cancer: Muscarinic receptors as new targets for tumor therapy. [PDF]

World J Clin Oncol, 2021
Español A, Salem A, Sanchez Y, Sales ME.   +3 more
europepmc   +1 more source

Comparative Sleep Architecture Profiles of Antidepressants in Mice: Pharmacological Characterization of Paroxetine, Sertraline, Duloxetine, Mirtazapine and Vortioxetine

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study compared five antidepressants (paroxetine, sertraline, duloxetine, mirtazapine, and vortioxetine) in mice using EEG/EMG, revealing distinct effects on REM and NREM sleep. The figure illustrates changes in sleep architecture during the light phase (ZT0–12).
Junya Maruoka, Ryo Egami, Yuto Akita, Kohei Kozuka, Yusuke Kakumoto, Tetsuro Kikuchi, Kazuhiko Kume   +6 more
wiley   +1 more source

Are there muscarinic receptors on erythrocyte membranes?

, 1983
Some investigators, utilizing electron spin resonance techniques or radiologic and binding assays, reported on the presence of muscarinic cholinergic receptors on the membranes of human erythrocytes. Recently, however, another report has questioned these
Murphy S. D., Costa L. G.
core  

The dual-site agonist for human M2 muscarinic receptors Iper-8-naphtalimide induces mitochondrial dysfunction in <i>Saccharomyces cerevisiae</i>. [PDF]

Microb Cell
Cirigliano A, Amelina A, Passarini E, Ricelli A, Balasco N, Mori M, Botta B, De Stefano ME, Papotto C, Guerriero C, Tata AM, Rinaldi T.   +11 more
europepmc   +1 more source

Balanced modulation of neuromuscular synaptic transmission via M1 and M2 muscarinic receptors during inhibition of cholinesterases. [PDF]

Sci Rep, 2022
Lenina OA, Petrov KA.
europepmc   +1 more source

Implementation of an Integrated Pharmacology Curriculum in a Flipped, Small‐Group, Case‐Based, Pre‐Clerkship Medical Curriculum Improved Student Performance

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric, Eric Van Rite, Lalita Prasad‐Reddy, Michael Bradaric   +3 more
wiley   +1 more source

Targeting muscarinic receptors in schizophrenia treatment: Novel antipsychotic xanomeline/trospium chloride. [PDF]

World J Psychiatry
Pejčić AV.
europepmc   +1 more source

Clemastine Promotes Differentiation of Oligodendrocyte Progenitor Cells Through the Activation of ERK1/2 via Muscarinic Receptors After Spinal Cord Injury. [PDF]

Front Pharmacol, 2022
Tong LY, Deng YB, Du WH, Zhou WZ, Liao XY, Jiang X.   +5 more
europepmc   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan, Katie Powell, Russ Chess‐Williams, Catherine McDermott   +3 more
wiley   +1 more source

Structure-guided engineering of snake toxins for selective modulation of adrenergic and muscarinic receptors. [PDF]

Nat Commun
Zhong Y, Tao H, Zhang Y, He B, Jiao H, Wang D, Teng M, Hu H, Guo Q, Tao Y.   +9 more
europepmc   +1 more source