Results 211 to 220 of about 52,654 (280)

Computational Quantification of Peristalsis in Preclinical Mouse Models Using Smartphone Videography

Neurogastroenterology &Motility, Volume 38, Issue 6, June 2026.
A new computational method and analytical pipeline for quantifying gut peristalsis in live mouse models that involves taking a video using a smartphone camera and then processing the videographic data using our custom analytical pipeline to quantify gastrointestinal motility.
Joseph C. Schindler, Gargi Vijayan Pillai, Thomas M. Raffay, Satish E. Viswanath, Puneet Seth   +4 more
wiley   +1 more source

Antiemetic activity of abietic acid possibly through the 5HT₃ and muscarinic receptors interaction pathways. [PDF]

Sci Rep
Hasan R, Alshammari A, Albekairi NA, Bhuia MS, Afroz M, Chowdhury R, Khan MA, Ansari SA, Ansari IA, Mubarak MS, Islam MT.   +10 more
europepmc   +1 more source

Functional Characterization of Muscarinic Receptors in Human Schwann Cells. [PDF]

Int J Mol Sci, 2020
Piovesana R, Faroni A, Tata AM, Reid AJ.
europepmc   +1 more source

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, Volume 111, Issue 6, Page 2987-2999, 1 June 2026.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

Further investigations on the influence of protein phosphatases on the signaling of muscarinic receptors in the atria of mouse hearts. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Gergs U, Wackerhagen S, Fuhrmann T, Schäfer I, Neumann J.   +4 more
europepmc   +1 more source

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition

The Journal of Physiology, Volume 604, Issue 12, Page 4984-5010, 15 June 2026.
Abstract figure legend Postsynaptic depolarisation and increases in intracellular Ca2+ ([Ca2+]i) trigger the synthesis of endocannabinoids (eCBs), which are hypothesised to enhance tonic GABAergic inhibition via two primary pathways. In the proposed autocrine mechanism, eCBs activate postsynaptic somatodendritic or mitochondrial CB1 receptors ...
Roberto Colangeli, Fiorenzo Conti
wiley   +1 more source

Parasympathetic overdrive as a cause of overactive bladder in a high‐fat‐diet‐induced obesity mouse model

The Journal of Physiology, Volume 604, Issue 12, Page 4945-4967, 15 June 2026.
Abstract figure legend Obesity and metabolic syndrome (MetS) are well‐known major risk factors for overactive bladder (OAB). Mechanisms underlying obesity‐/MetS‐associated OAB were explored using a high‐fat‐diet (HFD)‐induced obesity mouse model. HFD‐induced obesity/MetS mice developed an OAB phenotype characterized by enlarged non‐voiding contractions
Ayu Sugiura, Retsu Mitsui, Kyoko Miwa‐Nishimura, Hikaru Hashitani   +3 more
wiley   +1 more source

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source

Targeting the Actions of Muscarinic Receptors on Dopamine Systems: New Strategies for Treating Neuropsychiatric Disorders. [PDF]

Annu Rev Pharmacol Toxicol
Nunes EJ, Addy NA, Conn PJ, Foster DJ.
europepmc   +1 more source