Results 221 to 230 of about 2,360,825 (374)

The Interplay of Cross‐Organ Immune Regulation in Inflammation and Cancer

MedComm, Volume 6, Issue 7, July 2025.
Organs interact dynamically through immune regulation, influencing systemic immune responses and disease progression. We review molecular and cellular mechanisms of cross‐organ immune regulation in inflammation and cancer, focusing on gut, liver, and brain interactions with other organs.
Jie Dou, Jinzuo Jiang, Yangtao Xue, Xiaoqi Jiang, Yongzhuo Jiang, Peng Xiao, Junjie Xu   +6 more
wiley   +1 more source

Muscarinic Receptors and Alzheimer's Disease: New Perspectives and Mechanisms. [PDF]

Curr Issues Mol Biol
Monaco M, Trebesova H, Grilli M.
europepmc   +1 more source

Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting.

, 1985
Rafael Mattera, Barry J.R. Pitts, Mark L. Entman, Lutz Birnbaumer   +3 more
openalex   +1 more source

Immunologic mimicry by a monoclonal antibody of the tricyclic anti-depressants' binding site on muscarinic acetylcholine receptors. [PDF]

, 1987
Stéfano Marullo, Johan Hoebeke, J G Guillet, Carl André, A. Donny Strosberg   +4 more
openalex   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

Medicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni, Giulia Galli, Clelia Dallanoce, Marco De Amici, Pau Gorostiza, Carlo Matera   +5 more
wiley   +1 more source

Muscarinic receptors mediate motivation via preparatory neural activity in humans. [PDF]

Elife
Grogan JP, Raemaekers M, van Swieten MMH, Green AL, Gillies MJ, Manohar SG.   +5 more
europepmc   +1 more source

Intrahippocampal blockade of nicotinic or muscarinic receptors fails to impair nonnavigational spatial memory in macaques. [PDF]

Behav Neurosci, 2021
LaFlamme EM, Malkova L, Forcelli PA.
europepmc   +1 more source

Purification of the muscarinic acetylcholine receptor from porcine atria [PDF]

, 1984

openalex   +1 more source

Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95

Nature Neuroscience, 2010
J. Jo, G. H. Son, Bryony L. Winters, M. J. Kim, Daniel J. Whitcomb, Bryony A Dickinson, Youn-Bok Lee, K. Futai, M. Amici, M. Sheng, G. Collingridge, Kwangwook Cho   +11 more
semanticscholar   +1 more source

Piperazine Derivatives Attenuate Scopolamine‐Induced Memory Deficits by Modulating Neuroinflammation and Oxidative Stress via the NF‐κB/TNF‐α/COX‐2 Pathway

ChemistrySelect, Volume 10, Issue 25, July 4, 2025.
Piperazine derivatives 2b, 2f, and 2h reduce neuroinflammation, oxidative stress, and memory impairment by modulating COX‐2, p‐NF‐κB, and TNF‐α pathways, showing promise as lead compounds for neurodegenerative disease drug development. Abstract Oxidative stress‐induced neuro‐inflammatory events are common in neurodegenerative illnesses, addressing ...
Sadaf Fardoos, Sidra Kaleem, Syed Muzzammil Masaud, Faryal Jahan, Humaira Nadeem, Muhammad Afzal, Abdulwahed Fahad Alrefaei, Eman Alshehri, Sajid Ali   +8 more
wiley   +1 more source