Results 11 to 20 of about 425,571 (245)

Replenishing NAD+ content reduces aspects of striated muscle disease in a dog model of Duchenne muscular dystrophy

open access: yesSkeletal Muscle, 2023
Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in DMD gene and loss of the protein dystrophin, which ultimately leads to myofiber membrane fragility and necrosis, with eventual muscle atrophy and contractures.
Déborah Cardoso   +3 more
doaj   +1 more source

Resistance exercise training improves mucociliary clearance in subjects with COPD: A randomized clinical trial

open access: yesPulmonology, 2019
Introduction Elastic tubing was recently investigated as an alternative to the conventional resistance training (RT) in chronic obstructive pulmonary disease (COPD). The effects of RT on the mucociliary system have not yet been reported in the literature.
B.S.A. Silva   +7 more
doaj   +3 more sources

Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism

open access: yesSkeletal Muscle, 2020
Background Distal arthrogryposis (DA) is a group of autosomal dominant skeletal muscle diseases characterized by congenital contractures of distal limb joints.
Yiming Guo   +8 more
doaj   +1 more source

Redox proteomic analysis of the gastrocnemius muscle from adult and old mice

open access: yesData in Brief, 2015
The data provides information in support of the research article, “Differential Cysteine Labeling and Global Label-Free Proteomics Reveals an Altered Metabolic State in Skeletal Muscle Aging”, Journal of Proteome Research, 2014, 13 (11), 2008–21 [1]. Raw
Brian McDonagh   +4 more
doaj   +1 more source

Skeletal Muscle Physiology

open access: yesThe Scientific World Journal, 2013
In the beginning of the last century, muscle proteins were viewed as static structural molecules not capable of being utilized by other tissues or organs. This concept was accepted until the 30s, where Rudolf Schoenheimer presented strong evidences about the “Dynamic State of Body Constituents,” which means that skeletal muscle is not only capable of ...
Jacob M. Wilson   +3 more
openaire   +4 more sources

Autophagy in skeletal muscle [PDF]

open access: yesFEBS Letters, 2010
Muscle mass represents 40–50% of the human body and, in mammals, is one of the most important sites for the control of metabolism. Moreover, during catabolic conditions, muscle proteins are mobilized to sustain gluconeogenesis in the liver and to provide alternative energy substrates for organs.
openaire   +3 more sources

Skeletal Muscle Mitochondria and Aging: A Review

open access: yesJournal of Aging Research, 2012
Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines in skeletal muscle mitochondria are thought to play a primary role in this process.
Courtney M. Peterson   +2 more
doaj   +1 more source

Targeting healthspan to optimally combat non-communicable disease in an aging world

open access: yesSports Medicine and Health Science, 2019
Human lifespan and life expectancy have increased worldwide, but the number of years that we spend free of chronic or debilitating disorders, known as healthspan, has not shifted along with increased lifespan.
Joshua C. Drake, Zhen Yan
doaj   +1 more source

An updated C. elegans nuclear body muscle transcriptome for studies in muscle formation and function

open access: yesSkeletal Muscle, 2023
The body muscle is an important tissue used in organisms for proper viability and locomotion. Although this tissue is generally well studied and characterized, and many pathways have been elucidated throughout the years, we still lack a comprehensive ...
Anna L. Schorr   +3 more
doaj   +1 more source

Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling

open access: yesSkeletal Muscle, 2020
Background In Duchenne muscular dystrophy (DMD), DYSTROPHIN deficiency exposes myofibers to repeated cycles of contraction/degeneration, ultimately leading to muscle loss and replacement by fibrotic tissue.
Luca Caputo   +6 more
doaj   +1 more source

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