Results 11 to 20 of about 2,446,357 (366)

Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging

International Journal of Molecular Sciences, 2021
The maintenance of mitochondrial integrity is critical for muscle health. Mitochondria, indeed, play vital roles in a wide range of cellular processes, including energy supply, Ca2+ homeostasis, retrograde signaling, cell death, and many others.
J. Leduc‐Gaudet, S. Hussain, E. Barreiro, G. Gouspillou   +3 more
semanticscholar   +1 more source

Skeletal muscle ultrasound [PDF]

Neurological Research, 2011
Muscle ultrasound is a convenient technique to visualize normal and pathological muscle tissue as it is non-invasive and real-time. Neuromuscular disorders give rise to structural muscle changes that can be visualized with ultrasound: atrophy can be objectified by measuring muscle thickness, while infiltration of fat and fibrous tissue increases muscle
Pillen, S., Alfen, N. van
openaire   +4 more sources

Interactive Modelling of Volumetric Musculoskeletal Anatomy [PDF]

ACM Trans. Graph., Vol. 40, No. 4, Article 122. Publication date: August 2021, 2021
We present a new approach for modelling musculoskeletal anatomy. Unlike previous methods, we do not model individual muscle shapes as geometric primitives (polygonal meshes, NURBS etc.). Instead, we adopt a volumetric segmentation approach where every point in our volume is assigned to a muscle, fat, or bone tissue.
arxiv   +1 more source

Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis

Journal of Cachexia, Sarcopenia and Muscle, 2021
Satellite cells (SCs) are critical to skeletal muscle regeneration. Inactivation of SCs is linked to skeletal muscle loss. Transferrin receptor 1 (Tfr1) is associated with muscular dysfunction as muscle‐specific deletion of Tfr1 results in growth ...
Hongrong Ding, Shujie Chen, Xiaohan Pan, Xiaoshuang Dai, Guihua Pan, Ze Li, Xudong Mai, Ye Tian, Susu Zhang, Bingdong Liu, Guangchao Cao, Zhicheng Yao, Xiangping Yao, Liang Gao, Li Yang, Xiaoyan Chen, Jia Sun, Hong Chen, Mulan Han, Yulong Yin, Guohuan Xu, Huijun Li, Weidong Wu, Zheng Chen, Jingchao Lin, Liping Xiang, Jun Hu, Yan Lu, Xiao Zhu, Liwei Xie   +29 more
semanticscholar   +1 more source

Meeting report: the 2021 FSHD International Research Congress

Skeletal Muscle, 2022
Facioscapulohumeral muscular dystrophy (FSHD) is the second most common genetic myopathy, characterized by slowly progressing and highly heterogeneous muscle wasting with a typical onset in the late teens/early adulthood [1]. Although the etiology of the
Sujatha Jagannathan, Jessica C. de Greef, Lawrence J. Hayward, Kyoko Yokomori, Davide Gabellini, Karlien Mul, Sabrina Sacconi, Jamshid Arjomand, June Kinoshita, Scott Q. Harper   +9 more
doaj   +1 more source

Developing cardiac and skeletal muscle share fast-skeletal myosin heavy chain and cardiac troponin-I expression [PDF]

, 2012
Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate into fast skeletal muscle specific myosin heavy chain (sk-fMHC) and cardiac specific troponin-I (cTn-I) positive cells sustaining recipient myocardial ...
A Du, B Camoretti-Mercado, B Messner, Bradley B. Keller, C Cognard, CJ Sutherland, CS Rutland, D Pette, D Sassoon, F Fougerousse, F Pedrosa-Domellof, FS Apple, GE Lyons, H Oshima, Jason Tchao, JG Jacot, Johnny Huard, K Tobita, KC Clause, Kelly C. Clause, Kimimasa Tobita, L Saggin, L Saggin, Li J. Liu, LJ Sweeney, M Bahler, M Kawashima, M Okada, M Yasuda, Marie Jose Goumans, Mary C. Powell, N Hamalainen, R Di Lisi, RJ Solaro, S Fredericks, S Sartore, S Schiaffino, S Siedner, SK Bortolotto, V Haufe   +39 more
core   +7 more sources

Prions in skeletal muscle [PDF]

Proceedings of the National Academy of Sciences, 2002
Considerable evidence argues that consumption of beef products from cattle infected with bovine spongiform encephalopathy (BSE) prions causes new variant Creutzfeldt–Jakob disease. In an effort to prevent new variant Creutzfeldt–Jakob disease, certain “specified offals,” including neural and lymphatic tissues, thought to contain high ...
BOSQUE PJ, RYOU C, TELLING G, PERETZ D, Legname, Giuseppe, DEARMOND SJ, PRUSINER SB   +6 more
openaire   +2 more sources

Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy

Cells, 2020
Insulin-like growth factor-1 (IGF-1) is a key growth factor that regulates both anabolic and catabolic pathways in skeletal muscle. IGF-1 increases skeletal muscle protein synthesis via PI3K/Akt/mTOR and PI3K/Akt/GSK3β pathways. PI3K/Akt can also inhibit
Tadashi Yoshida, P. Delafontaine
semanticscholar   +1 more source

Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake.

Comprehensive Physiology, 2020
The skeletal muscle is the largest organ in the body, by mass. It is also the regulator of glucose homeostasis, responsible for 80% of postprandial glucose uptake from the circulation.
Karla E. Merz, D. Thurmond
semanticscholar   +1 more source

Denervation does not induce muscle atrophy through oxidative stress [PDF]

, 2017
Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness.
Adamo, Sergio, Bellezza, Ilaria, Fulle, Stefania, Greco, Emanuela, Grottelli, Silvia, Mancinelli, Rosa, Minelli, Alba, Moresi, Viviana, Morozzi, Giulio, Pigna, Eva, Rotini, Alessio   +10 more
core   +2 more sources