Results 41 to 50 of about 2,446,357 (366)
Molecular Metabolism, 2023 Objective: Glucocorticoids are one of the most commonly prescribed classes of anti-inflammatory drugs; however, chronic treatment promotes iatrogenic (drug-induced) diabetes.
Melissa A. Linden +10 more
doaj
Modelling and Analysis of Magnetic Fields from Skeletal Muscle for Valuable Physiological Measurements [PDF]
arXiv, 2021 MagnetoMyoGraphy (MMG) is a method of studying muscle function via weak magnetic fields generated from human active organs and tissues. The correspondence between MMG and electromyography means directly derived from the Maxwell-Amp\`ere law. Here, upon briefly describing the principles of voltage distribution inside skeletal muscles due to the ...
arxiv
Deep Proteomics of Mouse Skeletal Muscle Enables Quantitation of Protein Isoforms, Metabolic Pathways, and Transcription Factors [PDF]
, 2015 Skeletal muscle constitutes 40% of individual body mass and plays vital roles in locomotion and whole-body metabolism. Proteomics of skeletal muscle is challenging because of highly abundant contractile proteins that interfere with detection of ...
Cox, J. +5 more
core +1 more source
Myoblast fusion confusion: the resolution begins
Skeletal Muscle, 2018 The fusion of muscle precursor cells is a required event for proper skeletal muscle development and regeneration. Numerous proteins have been implicated to function in myoblast fusion; however, the majority are expressed in diverse tissues and regulate ...
Srihari C. Sampath +2 more
doaj +1 more source
Accelerated, physics-inspired inference of skeletal muscle microstructure from diffusion-weighted MRI [PDF]
arXiv, 2023 Muscle health is a critical component of overall health and quality of life. However, current measures of skeletal muscle health take limited account of microstructural variations within muscle, which play a crucial role in mediating muscle function. To address this, we present a physics-inspired, machine learning-based framework for the non-invasive ...
arxiv
Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases [PDF]
, 2014 Physical inactivity is a predisposing factor for various disease states including obesity, cardiovascular disease, as well as for certain types of cancer. Regular endurance exercise mediates several beneficial effects such as increased energy expenditure
Handschin, Christoph +1 more
core +1 more source
HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia [PDF]
, 2020 Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured.
Bonetto, Andrea +3 more
core +1 more source
Skeletal Muscle, 2012 Background Mice lacking MyoD exhibit delayed skeletal muscle regeneration and markedly enhanced numbers of satellite cells. Myoblasts isolated from MyoD-/- myoblasts proliferate more rapidly than wild type myoblasts, display a dramatic delay in ...
Parker Maura H +6 more
doaj +1 more source
The gut microbiota influences skeletal muscle mass and function in mice
Science Translational Medicine, 2019 Transplanting the gut microbiota of pathogen-free mice into germ-free mice improves skeletal muscle mass and strength. Of microbial metabolites and muscle Skeletal muscle is important not only for locomotion but also for regulating metabolic function ...
Shawon Lahiri +18 more
semanticscholar +1 more source
The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis
Skeletal Muscle, 2018 Background Members of the ZFP36 family of RNA-binding proteins regulate gene expression post-transcriptionally by binding to AU-rich elements in the 3’UTR of mRNA and stimulating mRNA degradation.
Hema Bye-A-Jee +6 more
doaj +1 more source