Results 41 to 50 of about 2,150,041 (199)
Guidance Molecules in Vascular Smooth Muscle
Frontiers in Physiology, 2018 Several highly conserved families of guidance molecules, including ephrins, Semaphorins, Netrins, and Slits, play conserved and distinct roles in tissue remodeling during tissue patterning and disease pathogenesis.
Alexandra Christine Finney +3 more
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Roles of Vascular Smooth Muscle Cells in Atherosclerotic Calcification
Journal of Lipid and Atherosclerosis, 2023 The accumulation of calcium in atherosclerotic plaques is a prominent feature of advanced atherosclerosis, and it has a strong positive correlation with the total burden of atherosclerosis.
Sang-Ho Woo, Dae-Yong Kim, Jae-Hoon Choi
doaj +1 more source
Calcium Dynamics in Vascular Smooth Muscle [PDF]
Microcirculation, 2013 AbstractSmooth muscle cells are ultimately responsible for determining vascular luminal diameter and blood flow. Dynamic changes in intracellular calcium are a critical mechanism regulating vascular smooth muscle contractility. Processes influencing intracellular calcium are therefore important regulators of vascular function with physiological and ...
Gregory C, Amberg, Manuel F, Navedo
openaire +2 more sources
Camphorated p-chlorophenol-induced contractile dynamics in aortic rings of Wistar rats
Revista Información Científica, 2021 Introduction: camphorated p-chlorophenol is a chlorophenolic derivative commonly used as an intra-oral medication in endodontics. Scientific reports on its effects in arterial vascular smooth muscle and local blood flow regulation are scarce. Objective:
Oscar Rodríguez-Reyes +4 more
doaj
Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk [PDF]
, 2012 We have previously shown that injury-induced neointima formation was rescued by adenoviral-Nogo-B gene delivery. Integrase-competent lentiviral vectors (ICLV) are efficient at gene delivery to vascular cells but present a risk of insertional mutagenesis.
Sessa, W.C. +10 more
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Frontiers in Physiology, 2017 There are two primary components that produce pulmonary arterial hypertension (PAH); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary ...
Melissa A. Lyle +2 more
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RhoA activation by hypoxia in pulmonary arterial smooth muscle cells is age and site specific [PDF]
, 2004 Hypoxia induces vasoconstriction of pulmonary arteries through contraction of smooth muscle cells (SMCs). The GTPase RhoA regulates smooth muscle contractility and actin cytoskeletal remodeling through the Rho-associated kinase ( ROCK).
Bailly, K +6 more
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TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms
JACC: Basic to Translational Science, 2023 Summary: Phenotypic switching of vascular smooth muscle cells is a central process in abdominal aortic aneurysm (AAA) pathology. We found that knockdown TCF7L1 (transcription factor 7-like 1), a member of the TCF/LEF (T cell factor/lymphoid enhancer ...
Jing Wang, MM +7 more
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The role of the notch signalling pathway in vascular smooth muscle cell apoptosis [PDF]
, 2004 The Notch signalling system is a highly conserved method of cell-to-cell communication involved in cell fate decisions in many cell types. Until recently, the importance of the Notch signalling pathway was recognized in the embryonic but not in the adult
Sweeney, Catherine Helena
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MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling.
PLoS Genetics, 2019 As small regulatory transcripts, microRNAs (miRs) act as genetic 'fine tuners' of posttranscriptional events, and as genetic switches to promote phenotypic switching. The miR miR26a targets the BMP signalling effector, smad1.
Charlene Watterston +3 more
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