Results 51 to 60 of about 297,987 (316)
URETHANE AND CONTRACTION OF VASCULAR SMOOTH MUSCLE [PDF]
British Journal of Pharmacology, 1979 In vitro studies were undertaken on rat aortic strips and portal vein segments in order to determine whether or not the anaesthetic, urethane, can exert direct actions on vascular smooth muscle. Urethane was found to inhibit development of spontaneous mechanical activity.
B M, Altura, J, Weinberg
openaire +2 more sources
Camphorated p-chlorophenol-induced contractile dynamics in aortic rings of Wistar rats
Revista Información Científica, 2021 Introduction: camphorated p-chlorophenol is a chlorophenolic derivative commonly used as an intra-oral medication in endodontics. Scientific reports on its effects in arterial vascular smooth muscle and local blood flow regulation are scarce. Objective:
Oscar Rodríguez-Reyes +4 more
doaj
Frontiers in Pharmacology, 2021 Rosmarinic acid is a natural phenolic acid and active compound found in many culinary plants, such as rosemary, mint, basil and perilla. Aiming to improve the pharmacokinetic profile of rosmarinic acid and its activity on vascular smooth muscle cell ...
Tina Blažević +7 more
doaj +1 more source
Nongenomic effects of aldosterone on phosphocreatine levels in human calf muscle during recovery from exercise. [PDF]
, 1996 Nongenomic in vitro effects of aldosterone on the sodium-proton antiport and intracellular second messengers have been described in human mononuclear leukocytes, vascular smooth muscle cells, and endothelial cells.
Wehling, Martin +10 more
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Frontiers in Physiology, 2017 There are two primary components that produce pulmonary arterial hypertension (PAH); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary ...
Melissa A. Lyle +2 more
doaj +1 more source
Serotonylation of vascular proteins important to contraction. [PDF]
PLoS ONE, 2009 BACKGROUND:Serotonin (5-hydroxytryptamine, 5-HT) was named for its source (sero-) and ability to modify smooth muscle tone (tonin). The biological effects of 5-HT are believed to be carried out by stimulation of serotonin receptors at the plasma membrane.
Stephanie W Watts +2 more
doaj +1 more source
Endothelial cell impact on smooth muscle cell properties: role of hemodynamic forces [PDF]
, 2009 The vascular endothelium is a dynamic cell monolayer located at the interface of the vessel wall and bloodstream, where it regulates the physiological effects of humoral and hemodynamic stimuli on vessel tone and remodelling.
Killeen, Maria T.
core
, 1991 Primary ciliary muscle cell cultures derived from human donors (16-91 years) were established and characterized by comparing them with ciliary muscle in tissue sections using immunocytochemical and ultrastructural methods.
Baur, A. +3 more
core +1 more source