Results 31 to 40 of about 2,150,041 (199)

Endothelial cell-derived extracellular vesicles alter vascular smooth muscle cell phenotype through high-mobility group box proteins

Journal of Extracellular Vesicles, 2020
The vascular endothelium and smooth muscle form adjacent cellular layers that comprise part of the vascular wall. Each cell type can regulate the other’s structure and function through a variety of paracrine effectors.
Michael J. Boyer, Yayoi Kimura, Tomoko Akiyama, Ariele Y. Baggett, Kyle J. Preston, Rosario Scalia, Satoru Eguchi, Victor Rizzo   +7 more
doaj   +1 more source

The vascular renin-angiotensin-aldosterone system [PDF]

, 2001
PhDThe renin-angiotensin-aldosterone system (RAAS) is one of the major regulators of blood pressure. The actions and generation of RAAS components at the tissue level are less well appreciated.
Xiao, Fang
core   +4 more sources

Smooth muscle cells largely develop independently of functional hemogenic endothelium

Stem Cell Research, 2014
Vascular smooth muscle cells represent a major component of the cardiovascular system. In vitro studies have shown that FLK1+ cells derived from embryonic stem (ES) cells can differentiate into both endothelial and smooth muscle cells.
Monika Stefanska, Guilherme Costa, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud   +4 more
doaj   +1 more source

Angiomyoma: An Unusual Diagnosis of Preauricular Swelling [PDF]

Journal of Clinical and Diagnostic Research, 2018
Angiomyoma is a benign tumour arising from smooth muscle of blood vessel walls. These tumours are usually found in the lower extremities presenting as a painful mass.
Anamika Kashyap, Smita Singh, Kiran Agarwal   +2 more
doaj   +1 more source

Gasdermin D affects aortic vascular smooth muscle cell pyroptosis and Ang II-induced vascular remodeling

Heliyon, 2023
Vascular smooth muscle cells (VSMCs) are primarily responsible for vasoconstriction and the regulation of blood pressure1. Pyroptosis, a particular form of regulated cell death, is involved in multiple vascular injuries, including hypertensive vascular ...
Zimin Fang, Gaojun Wu, Jian Sheng, Bozhi Ye, Zhouqing Huang, Jianjiang Xu, Jianqin Zhang, Jibo Han, Bingjiang Han, Jiajun Xu   +9 more
doaj   +1 more source

Endothelial cell impact on smooth muscle cell properties: role of hemodynamic forces [PDF]

, 2009
The vascular endothelium is a dynamic cell monolayer located at the interface of the vessel wall and bloodstream, where it regulates the physiological effects of humoral and hemodynamic stimuli on vessel tone and remodelling.
Killeen, Maria T.
core   +2 more sources

Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics [PDF]

, 1991
Primary ciliary muscle cell cultures derived from human donors (16-91 years) were established and characterized by comparing them with ciliary muscle in tissue sections using immunocytochemical and ultrastructural methods.
Baur, A., Tamm, Ernst R., Flügel, C., Lütjen-Drecoll, E.   +3 more
core   +1 more source

Depletion of Mitochondrial Cyclophilin D in Endothelial and Smooth Muscle Cells Attenuates Vascular Dysfunction and Hypertension

Function
Hypertension is a major risk factor of cardiovascular disease affecting nearly half of adult population. It is associated with mitochondrial dysfunction and understanding these mechanisms is important to develop new therapies.
Anna Dikalova, Mingfang Ao, Louise Lantier, Sergey Gutor, Sergey Dikalov   +4 more
doaj   +1 more source

Vascular smooth muscle cells in atherosclerosis [PDF]

Nature Reviews Cardiology, 2019
Vascular smooth muscle cells (VSMCs) are a major cell type present at all stages of an atherosclerotic plaque. According to the 'response to injury' and 'vulnerable plaque' hypotheses, contractile VSMCs recruited from the media undergo phenotypic conversion to proliferative synthetic cells that generate extracellular matrix to form the fibrous cap and ...
Basatemur, Gemma L, Jørgensen, Helle F, Clarke, Murray CH, Bennett, Martin R, Mallat, Ziad   +4 more
openaire   +3 more sources

Caveolin-3 promotes a vascular smooth muscle contractile phenotype

Frontiers in Cardiovascular Medicine, 2015
Epidemiological studies have demonstrated the importance of cardiovascular diseases in Western countries. Among the cell types associated with a dysfunctional vasculature, smooth muscle cells are believed to play an essential role in the development of ...
Jorge L. Gutierrez-Pajares, Jeannette eIturrieta, Vipin eDulam, Yu eWang, Yu eWang, Stephanos ePavlides, Gabriella eMalacari, Michael P. Lisanti, Philippe G. Frank   +8 more
doaj   +1 more source