Results 71 to 80 of about 1,375,049 (303)

The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition [PDF]

, 2010
Many disease states are associated with regional or systemic hypoxia. The study of healthy individuals exposed to high-altitude hypoxia offers a way to explore hypoxic adaptation without the confounding effects of disease and therapeutic interventions ...
Grocott Mike P., Edwards, Lindsay M, Holloway, CJ, Mike P Grocott, Grocott, Mike P, Edwards, LM, Neubauer, Stefan, Hugh E Montgomery, Murray Andrew J., Peter A Robbins, Robbins Peter A., Robbins, Peter A., Montgomery, Hugh E., Robbins, Peter A, Grocott, Mike P.W., Tyler Damian J., Earnest, Conrad P., Holloway Cameron J., Damian J Tyler, Murray, Andrew J, Caudwell Xtreme Everest Research Group, Clarke Kieran, Montgomery, Hugh E, Kemp Graham J., Andrew J Murray, Murray, AJ, ?, ?, Neubauer Stefan, Clarke, K, Robbins, Peter, Denny Levett, Holloway, Cameron J, Holloway, Cameron J., Kieran Clarke, Graham J Kemp, Montgomery Hugh E., Murray, Andrew J., Grocott, Mike P., Levett Denny, Grocott, MP, Caudwell Xtreme Everest Res Grp, Lindsay M Edwards, Tyler, Damian, Robbins, PA, Edwards, Lindsay M., Kemp, Graham J, Montgomery, HE, Tyler, Damian J, Levett, D, Kemp, Graham J., Neubauer, S, Tyler, DJ, Kemp, GJ, Levett, Denny, Clarke, Kieran, Cameron J Holloway, Tyler, Damian J., Stefan Neubauer, Edwards Lindsay M.   +58 more
core   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Role of Myofibrillar Protein Catabolism in Development of Glucocorticoid Myopathy: Aging and Functional Activity Aspects

Metabolites, 2016
Muscle weakness in corticosteroid myopathy is mainly the result of the destruction and atrophy of the myofibrillar compartment of fast-twitch muscle fibers.
Teet Seene, Priit Kaasik
doaj   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

Nuclear receptors and skeletal muscle fiber type

Journal of Physical Fitness and Sports Medicine, 2015
The contractile and metabolic properties of skeletal muscle depend on muscle fiber type composition. There are two major fiber types: type 1 fibers (slow-twitch oxidative) and type 2 fibers (fast-twitch glycolytic).
Wataru Mizunoya
doaj   +1 more source

The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo [PDF]

, 2015
The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is abundantly expressed in trained muscles and regulates muscle adaptation to endurance exercise. Inversely, mice lacking a functional PGC-1α allele in muscle exhibit reduced muscle
Handschin, Christoph, Christoph Handschin, Regula Furrer, Furrer, Regula, Eisele, Petra Sabine, Markus Beer, Beer, Markus, Petra Sabine Eisele   +7 more
core   +1 more source

Inductively Expandable Supraparticles as Microscopic Force Generators for Remote Mechanical Actuation

Advanced Materials, EarlyView.
This study demonstrates the combination of magnetic nanoparticles and functional blowing agents into supraparticles. Upon induction heating, they actuate via rapid gas generation or extensive volume expansion. These supraparticles lift up to 25 000 times their own mass and rapidly open cured epoxy resins, providing a versatile strategy for fast micron ...
Leoni Luthardt, Stephan Müssig, Robert Luxenhofer, Karl Mandel   +3 more
wiley   +1 more source

Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres [PDF]

, 1989
The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as K+ channel openers, on the electrical activity of human skeletal muscle.
Lehmann-Horn, Frank, Grafe, Peter, Spuler, A.   +2 more
core   +1 more source

Soft Actuators Integrated with Control and Power Units: Approaching Wireless Autonomous Soft Robots

Advanced Robotics Research, EarlyView.
Soft robots exhibit significant development potential in various applications. However, there are still key technical challenges regarding material improvement, structure design and components integration. This review focuses on the development and challenge of soft actuators, power components, and control components in untethered intelligent soft ...
Renwu Shi, Feifei Pan, Xiaobin Ji
wiley   +1 more source

Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice [PDF]

, 2014
Pharmacokinetics and effects on skeletal muscle and physical performance of oral acetylcarnitine and propionylcarnitine are not well characterized. We therefore investigated the influence of oral acetylcarnitine, propionylcarnitine, and carnitine on body
Morand, Réjane, Handschin, Christoph, Hench, Jürgen, Felser, Andrea, Krähenbühl, Stephan, Bouitbir, Jamal, Frank, Stephan   +6 more
core   +1 more source