Results 51 to 60 of about 98,011 (316)

Noninvasive Estimation of Myosin Heavy Chain Composition in Human Skeletal Muscle

, 2011
Purpose: Information on muscle fiber type composition is of great importance in muscle physiology and athletic performance. Because there are only a few techniques available that noninvasively and accurately provide an estimate of muscle fiber type ...
Rittweger, Jörn, JÖRN RITTWEGER, IGOR B. MEKJAVIĆ, Pisot, Rado, BOŠTJAN ŠIMUNIČ, Degens, Hans, Narici, M., Mekjavic, Igor, RADO PIŠOT, Pišot, R., MARCO NARICI, Degens, H., Simunic, Bostjan, Simunič, B., HANS DEGENS, Narici, Marco, Mekjavić, I. B., Rittweger, J.   +17 more
core   +1 more source

Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice [PDF]

, 2014
Pharmacokinetics and effects on skeletal muscle and physical performance of oral acetylcarnitine and propionylcarnitine are not well characterized. We therefore investigated the influence of oral acetylcarnitine, propionylcarnitine, and carnitine on body
Morand, Réjane, Handschin, Christoph, Hench, Jürgen, Felser, Andrea, Krähenbühl, Stephan, Bouitbir, Jamal, Frank, Stephan   +6 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Drug Effect Unveils Inter-head Cooperativity and Strain-dependent ADP Release in Fast Skeletal Actomyosin [PDF]

, 2009
Amrinone is a bipyridine compound with characteristic effects on the force-velocity relationship of fast skeletal muscle, including a reduction in the maximum shortening velocity and increased maximum isometric force.
Torres, Nuria Albet,, Geeves, M., Barman, T., Barman, Tom, Bloemink, Marieke J, Schmitz, S, Piperio, C., Lionne, C, Albet-Torres, Nuria, Schmitz, Stephan, Bloemink, Marieke J., Golker, K., Bloemink, M., Candau, R., Veigel, C., Herrmann, Christian, Albet-Torres, N., Geeves, Michael A, Mansson, A., Mansson, Alf, Herrmann, C., Månsson, Alf,, Piperio, C, Candau, Robin, Geeves, Michael A., Herrmann, C, Frölander, Kerstin,, Schmitz, S., Candau, R, Piperio, Claudia, Lionne, Corinne, Veigel, Claudia, Bloemink, MJ, Geeves, MA, Frolander, K., Lionne, C., Golker, Kerstin, Frolander, Kerstin, Veigel, C, Golker, Kerstin,, Barman, T   +40 more
core   +1 more source

The Diversity of Skeletal Muscle Fiber Types

Cold Spring Harbor Perspectives in Biology
The widespread presence of slow-red and fast-white muscles in all vertebrates supports the evolutionary advantage of having two types of motors available for animal movement-a slow economical motor used for most activities, and a fast energetically costly motor used for rapid movements and emergency actions, and actions that require a lot of force ...
Schiaffino, Stefano, Chemello, Francesco, Reggiani, Carlo   +2 more
openaire   +3 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The slow sarco/endoplasmic reticulum Ca2+-ATPase declines independently of slow myosin in soleus muscle of diabetic rats [PDF]

, 2009
The sarcoplasmic reticulum Ca2+-ATPase (SERCA) isoforms are normally expressed in coordination with the corresponding myosin heavy chain (MyHC) isoforms in the fibers of skeletal muscle but this coordination is often disrupted in pathological conditions.
Rácz, Gábor, Rácz Gábor, Zádor, Ernő, Szabó Andrea Zsófia, Vér Ágota, Vér, Ágota, Szabó, András, Zádor Ernő   +7 more
core  

Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers

Scientific Reports, 2022
The sarcomere is the functional unit of skeletal muscle, essential for proper contraction. Numerous acquired and inherited myopathies impact sarcomere function causing clinically significant disease.
Ashley A. Martin, Brian R. Thompson, Jonathan P. Davis, Hluechy Vang, Dongwoo Hahn, Joseph M. Metzger   +5 more
doaj   +1 more source

HDAC4 Knockdown Alleviates Denervation-Induced Muscle Atrophy by Inhibiting Myogenin-Dependent Atrogene Activation

Frontiers in Cellular Neuroscience, 2021
Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy. Histone deacetylase 4 (HDAC4) has recently been found to be closely related
Wenjing Ma, Yong Cai, Yuntian Shen, Xin Chen, Lilei Zhang, Yanan Ji, Zehao Chen, Jianwei Zhu, Xiaoming Yang, Hualin Sun   +9 more
doaj   +1 more source