Measurement of Myoplasmic Calcium Transients in Mouse Slow-Twitch Muscle Fibers [PDF]
Bundles of intact fibers from soleus muscles of adult mice were isolated by dissection and one fiber within a bundle was micro-injected with either furaptra or mag-fluo-4, two low-affinity rapidly-responding Ca2+ indicators. Fibers were activated by action potentials to elicit changes in indicator fluorescence (dF), a monitor of the myoplasmic free Ca2+
Hollingworth, Stephen +2 more
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Slow-Twitch Fiber Proportion in Skeletal Muscle Correlates With Insulin Responsiveness [PDF]
The metabolic syndrome, characterized by central obesity with dyslipidemia, hypertension, and hyperglycemia, identifies people at high risk for type 2 diabetes.Our objective was to determine how the insulin resistance of the metabolic syndrome is related to muscle fiber composition.Thirty-nine sedentary men and women (including 22 with the metabolic ...
Stuart, Charles A. +7 more
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Coexistence of two calsequestrin isoforms in rabbit slow‐twitch skeletal muscle fibers [PDF]
The cardiac and skeletal muscle isoforms of calsequestrin (CS), the low affinity, high capacity Ca2+ binding protein localized in the lumen of sarcoplasmic reticulum, are the products of two different genes (Fliegel, L., Leberer, E., Green, N.M. and MacLennan, D.H. (1982) FEBS Lett.
Biral, Donatella +3 more
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25-Hydroxyvitamin D<sub>3</sub> promotes slow-twitch fiber type transition in skeletal muscle. [PDF]
Park MY +4 more
europepmc +3 more sources
The enzymatic complex Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase (NOx) may be the principal source of reactive oxygen species (ROS). The NOX2 and NOX4 isoforms are tissue-dependent and are differentially expressed in slow-twitch fibers ...
Juliana Osório Alves +10 more
doaj +1 more source
The effect of breed and body weight at slaughter on histochemical muscle fiber characteristics and meat quality of longissimus lumborum and semitendinosus lamb muscles [PDF]
The skeletal muscles of mammals are composed of fibers of different morphological, metabolic and functional characteristics. The properties of muscle fibers may be determined genetically as well as by environmental factors such as the age of the animals,
W. Rant, A. Radzik-Rant
doaj +1 more source
Bayberry is known to be a rich source of natural flavonoids and has been reported to have various health-promoting abilities. However, its function on regulating skeletal muscle fiber type remains unclear.
Jinjie Li +5 more
doaj +1 more source
Size and Proportions of Slow-Twitch and Fast-Twitch Muscle Fibers in Human Costal Diaphragm [PDF]
Smaller diaphragmatic motor unit potentials (MUPs) compared to MUPs of limb muscles lead to the hypothesis that diaphragmatic muscle fibers, being the generators of MUPs, might be also smaller. We compared autopsy samples of costal diaphragm and vastus lateralis of healthy men with respect to fibers’ size and expression of slow myosin heavy chain ...
Marija Meznaric, Erika Cvetko
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LncRNA-FKBP1C regulates muscle fiber type switching by affecting the stability of MYH1B
Long non-coding RNAs (lncRNAs) are well-known to participate in a variety of important regulatory processes in myogenesis. In our previous RNA-seq study (accession number GSE58755), we found that lncRNA-FKBP1C was differentially expressed between White ...
Jia-ao Yu +5 more
doaj +1 more source
Diaphragm assessment in mice overexpressing phospholamban in slow‐twitch type
AbstractAimsPhospholamban (PLN) and sarcolipin (SLN) are small inhibitory proteins that regulate the sarco(endo)plasmic reticulum Ca2+‐ATPase (SERCA) pump. Previous work from our laboratory revealed that in the soleus and gluteus minimus muscles of mice overexpressing PLN (PlnOE), SERCA function was impaired, dynamin 2 (3–5 fold) and SLN (7–9 fold ...
Fajardo, Val Andrew +5 more
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