COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022 Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley +1 more source
Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. [PDF]
PLoS ONE, 2011 Determining the sub-cellular localization of a protein within a cell is often an essential step towards understanding its function. In Caenorhabditis elegans, the relatively large size of the body wall muscle cells and the exquisite organization of their
Barbara Meissner +8 more
doaj +1 more source
Insomnia impairs muscle function via regulating protein degradation and muscle clock [PDF]
arXiv, 2023 Background: Insomnia makes people more physically unable of doing daily duties, which results in a lack of strength, leads to lacking in strength. However, the effects of insomnia on muscle function have not yet been thoroughly investigated. So, the objectives of this study were to clarify how insomnia contributes to the decrease of muscular function ...
arxiv
Chemical Relaxation of a Binary Mechanical Model System [PDF]
, 2022 With potential relevance to biomechanics, an interesting problem in statistical mechanics not previously solved is a binary mechanical model system. Discrete chemical states of proteins are often associated with discrete metastable structural states, such that with a change in state a protein acts as a molecular switch.
arxiv +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022 Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls +9 more
wiley +1 more source
Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]
PLoS ONE, 2014 Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi +4 more
doaj +1 more source
Mechanics, Energetics, Entropy and Kinetics of a Binary Mechanical Model System [PDF]
, 2022 With the formal construction of a thermodynamic spring, I describe the mechanics, energetics, entropy, and kinetics of a binary mechanical model system. A protein that transitions between two metastable structural states behaves as a molecular switch, and an ensemble of molecular switches that displace compliant elements equilibrated with a system ...
arxiv +1 more source
Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis [PDF]
G. Celli\`ere, D Menshykau and Dagmar Iber (2012) Biology Open 1,
775-788, 2012 Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature. Lung branching morphogenesis is strongly stereotyped and involves the recursive use of only three modes of branching.
arxiv +1 more source
Identification of proteins from interstitium of trapezius muscle in women with chronic myalgia using microdialysis in combination with proteomics. [PDF]
PLoS ONE, 2012 BACKGROUND: Microdialysis (MD) of the trapezius muscle has been an attractive technique to investigating small molecules and metabolites in chronic musculoskeletal pain in human. Large biomolecules such as proteins also cross the dialysis membrane of the
Patrik Olausson +4 more
doaj +1 more source
Proteomic Analysis of Chicken Skeletal Muscle during Embryonic Development
Frontiers in Physiology, 2017 Embryonic growth and development of skeletal muscle is a major determinant of muscle mass, and has a significant effect on meat production in chicken. To assess the protein expression profiles during embryonic skeletal muscle development, we performed a ...
Hongjia Ouyang +11 more
doaj +1 more source