Results 31 to 40 of about 7,390,925 (358)

Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy

Skeletal Muscle, 2013
BackgroundThe childhood neuromuscular disease spinal muscular atrophy (SMA) is caused by mutations or deletions of the survival motor neuron (SMN1) gene.
Justin G. Boyer, L. Murray, Kyle Scott, Y. De Repentigny, J. Renaud, R. Kothary   +5 more
semanticscholar   +1 more source

Influence of high pre-rigor temperature and fast pH fall on muscle proteins and meat quality: a review

, 2014
The impacts of accelerated pH decline combined with high muscle temperature on post-mortem muscle metabolism and subsequent meat quality attributes have been extensively studied. Traditionally, this phenomenon has been observed in pork muscles, primarily
Y. H. Kim, R. Warner, K. Rosenvold
semanticscholar   +1 more source

Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]

PLoS ONE, 2014
Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi, Xiaochun Long, Allison Hendershot, Joseph M Miano, Jane Sottile   +4 more
doaj   +1 more source

Do muscle fiber conduction slowing and decreased levels of circulating muscle proteins represent sensitive markers of steroid myopathy? A pilot study in Cushing's disease.

European Journal of Endocrinology, 2011
OBJECTIVE Glucocorticoids are known to decrease protein synthesis and conduction velocity of muscle fibers. However, the degree of impairment of muscle protein synthesis and conduction slowing in patients with Cushing's disease remains poorly ...
M. Minetto, F. Lanfranco, A. Botter, G. Motta, G. Mengozzi, R. Giordano, A. Picu, E. Ghigo, E. Arvat   +8 more
semanticscholar   +1 more source

Sarcopenia: Aging-Related Loss of Muscle Mass and Function.

Physiological Reviews, 2019
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility, diminishes quality of life, and can lead to fall-related injuries, which require costly hospitalization and extended rehabilitation.
L. Larsson, H. Degens, Meishan Li, L. Salviati, Young Il Lee, W. Thompson, J. Kirkland, M. Sandri   +7 more
semanticscholar   +1 more source

Proteomic Analysis of Chicken Skeletal Muscle during Embryonic Development

Frontiers in Physiology, 2017
Embryonic growth and development of skeletal muscle is a major determinant of muscle mass, and has a significant effect on meat production in chicken. To assess the protein expression profiles during embryonic skeletal muscle development, we performed a ...
Hongjia Ouyang, Hongjia Ouyang, Zhijun Wang, Zhijun Wang, Xiaolan Chen, Xiaolan Chen, Jiao Yu, Jiao Yu, Zhenhui Li, Zhenhui Li, Qinghua Nie, Qinghua Nie   +11 more
doaj   +1 more source

Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids.

American Journal of Clinical Nutrition, 2005
BACKGROUND Previous evidence suggests that aging in healthy persons does not result in decreased incorporation of muscle proteins after a bolus ingestion of 15 g essential amino acids (EAAs).
C. Katsanos, Hisamine Kobayashi, M. Sheffield-Moore, A. Aarsland, R. Wolfe   +4 more
semanticscholar   +1 more source

Expression profiles of muscle disease-associated genes and their isoforms during differentiation of cultured human skeletal muscle cells

BMC Musculoskeletal Disorders, 2012
Background The formation of contractile myofibrils requires the stepwise onset of expression of muscle specific proteins. It is likely that elucidation of the expression patterns of muscle-specific sarcomeric proteins is important to understand muscle ...
Abdul-Hussein Saba, van der Ven Peter F M, Tajsharghi Homa   +2 more
doaj   +1 more source

Changes in basal and insulin and amino acid response of whole body and skeletal muscle proteins in obese men.

Journal of Clinical Endocrinology and Metabolism, 2009
CONTEXT Obesity-related insulin resistance of glucose and lipid metabolism may also affect protein kinetics, notably at the muscle level. OBJECTIVE We hypothesized that muscle protein response to insulin and amino acid is blunted during obesity ...
C. Guillet, I. Delcourt, M. Rance, C. Giraudet, S. Walrand, M. Bedu, P. Duché, Y. Boirie   +7 more
semanticscholar   +1 more source

Effects of Low-Load Blood Flow Restriction Training on Muscle Anabolism Biomarkers and Thrombotic Biomarkers Compared with Traditional Training in Healthy Adults Older Than 60 Years: Systematic Review and Meta-Analysis

Life
The aim of this meta-analysis was to determine the effects of low-load blood flow restriction training (LL-BFRT) on muscle anabolism and thrombotic biomarkers compared with the effects of traditional LL training and to analyse the changes in these ...
Raúl Fabero-Garrido, Miguel Gragera-Vela, Tamara del Corral, Marta Hernández-Martín, Gustavo Plaza-Manzano, Ibai López-de-Uralde-Villanueva   +5 more
doaj   +1 more source