Results 261 to 270 of about 481,133 (304)
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2018
Satellite cells (SCs) are a population of muscle-resident stem cells that are essential for efficient tissue repair. SCs reside in a relatively quiescent state during normal tissue turnover, but are activated in response to injury through the microenvironment and cell-intrinsic signals. During aging, SC dysfunction is a major contributor to the decline
Ara B, Hwang, Andrew S, Brack
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Satellite cells (SCs) are a population of muscle-resident stem cells that are essential for efficient tissue repair. SCs reside in a relatively quiescent state during normal tissue turnover, but are activated in response to injury through the microenvironment and cell-intrinsic signals. During aging, SC dysfunction is a major contributor to the decline
Ara B, Hwang, Andrew S, Brack
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Adult Skeletal Muscle Stem Cells
2014Skeletal muscles in vertebrates have a phenomenal regenerative capacity. A muscle that has been crushed can regenerate fully both structurally and functionally within a month. Remarkably, efficient regeneration continues to occur following repeated injuries.
Ramkumar Sambasivan, Shahragim Tajbakhsh
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Skeletal Muscle Stem Cells for Muscle Regeneration
2014Adult skeletal muscle possesses remarkable regenerative capacity. Muscle regeneration is mediated by a rare population of muscle stem cells that reside between the basal lamina and sarcolemma of muscle fibers. Due to their anatomical location, muscle stem cells have been coined satellite cells.
Johnny, Kim, Thomas, Braun
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2020
Myogenesis is the formation of skeletal muscle. Pioneering findings addressing the control of myogenesis are paradigmatic for numerous molecular control processes in developmental and cell biology, including stem cell biology and tissue regeneration.
Beate Brand-Saberi, Eric Bekoe Offei
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Myogenesis is the formation of skeletal muscle. Pioneering findings addressing the control of myogenesis are paradigmatic for numerous molecular control processes in developmental and cell biology, including stem cell biology and tissue regeneration.
Beate Brand-Saberi, Eric Bekoe Offei
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Muscle‐derived stem cells: Potential for muscle regeneration
Birth Defects Research Part C: Embryo Today: Reviews, 2003AbstractDuchenne muscular dystrophy (DMD) is a devastating X‐linked muscle disease characterized by progressive muscle weakness caused by the lack of dystrophin expression at the sarcolemma of muscle fibers. Although various approaches to delivering dystrophin in dystrophic muscle have been investigated extensively (e.g., cell and gene therapy), there ...
Johnny, Huard +2 more
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Adult Stem Cells: Adult Skeletal Muscle Stem Cells
2013Maintenance, repair and regeneration of adult skeletal muscle are mediated by stem or precursor cells within the muscle. In addition to the satellite cell, which is the archetypal muscle stem cell, there are other stem cells within skeletal muscle that can contribute to muscle regeneration under experimental conditions.
Jinhong Meng, Jennifer E. Morgan
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Ageing Skeletal Muscle: The Ubiquitous Muscle Stem Cell
2023In 1999, in a review by Beardsley, the potential of adult stem cells, in repair and regeneration was heralded (Beardsley Sci Am 281:30-31, 1999). Since then, the field of regenerative medicine has grown exponentially, with the capability of restoring or regenerating the function of damaged, diseased or aged human tissues being an underpinning ...
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Stem cell therapies for muscle disorders
Current Opinion in Neurology, 2012This review focuses on stem cell-based therapies to treat skeletal muscle disorders, with a special emphasis on muscular dystrophies.We briefly review previous attempts at cell therapy by the use of donor myoblasts, explaining the likely reasons for the poor clinical results; we then describe the use of the same cells in current promising trials for ...
Francesco S. Tedesco, Giulio Cossu
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Regulation of muscle stem cell function
2021Regeneration of skeletal muscle is a finely tuned process which is depending on muscle stem cells, a population of stem cells in skeletal muscle which is also termed satellite cells. Muscle stem cells are a prerequisite for regeneration of skeletal muscle.
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Current topics in developmental biology, 1999
Skeletal muscle development requires the formation of myoblasts that can fuse with each other to form multinucleate myofibers. Distinct primary and secondary, slow and fast, populations of myofibers form by the time of birth. At embryonic, fetal, and perinatal stages of development, temporally distinct lineages of myogenic cells arise and contribute to
J B, Miller, L, Schaefer, J A, Dominov
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Skeletal muscle development requires the formation of myoblasts that can fuse with each other to form multinucleate myofibers. Distinct primary and secondary, slow and fast, populations of myofibers form by the time of birth. At embryonic, fetal, and perinatal stages of development, temporally distinct lineages of myogenic cells arise and contribute to
J B, Miller, L, Schaefer, J A, Dominov
openaire +1 more source