Results 81 to 90 of about 3,255,580 (393)

Multi-functional dielectric elastomer artificial muscles for soft and smart machines

, 2012
Dielectric elastomer (DE) actuators are popularly referred to as artificial muscles because their impressive actuation strain and speed, low density, compliant nature, and silent operation capture many of the desirable physical properties of muscle ...
I. Anderson, T. Gisby, T. McKay, Benjamin M. O’Brien, E. Calius   +4 more
semanticscholar   +1 more source

The number and choice of muscles impact the results of muscle synergy analyses

Frontiers in Computational Neuroscience, 2013
One theory for how humans control movement is that muscles are activated in weighted groups or synergies. Studies have shown that electromyography (EMG) from a variety of tasks can be described by a low-dimensional space thought to reflect synergies ...
K. Steele, M. Tresch, E. Perreault
semanticscholar   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

PRKAG2 Variant, Motor Neuron Disease, and Parkinsonism: Fortuitous Association or a Potentially Underestimated Pathophysiological Mechanism?

Muscles
A 72-year-old Brazilian woman presented with a 4-year history of rest tremors of the hands, followed by slowness of movement, and a diagnosis of idiopathic Parkinson’s disease. She was started on dopamine agonists with significant improvement.
Marco Orsini, Wladimir Bocca Vieira de Rezende Pinto, Paulo Sgobbi, Acary Souza Bulle Oliveira   +3 more
doaj   +1 more source

The Organization and Role During Locomotion of the Proximal Musculature of the Cricket Foreleg : I. Anatomy and Innervation [PDF]

, 1986
The structure of the proximal segments of the cricket (Gryllus bimaculatus) foreleg, together with the associated musculature and its innervation are described.
Laurent, Gilles, Richard, Daniel
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Kinematic, Neuromuscular and Bicep Femoris In Vivo Mechanics during the Nordic Hamstring Exercise and Variations of the Nordic Hamstring Exercise

Muscles
The Nordic hamstring exercise (NHE) is effective at decreasing hamstring strain injury risk. Limited information is available on the in vivo mechanics of the bicep femoris long head (BFLH) during the NHE.
Nicholas Ripley, Jack Fahey, Paul Comfort, John McMahon   +3 more
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Examination of Sex-Related Differences in Fatigability and Frequency Components of Mechanomyographic Signals During Sustained Exercise

Muscles
Background: Surface mechanomyographic (sMMG) signals have been used to examine sex-specific differences in the mechanical behavior of muscle during fatiguing exercise.
Brian Benitez, Minyoung Kwak, Pasquale J. Succi, Clara J. Mitchinson, Haley C. Bergstrom   +4 more
doaj   +1 more source

Muscle Function and Fatigability of Trunk Flexors in Males and Females [PDF]

, 2017
Background Optimal function of the abdominal muscles is necessary for several life functions including lifting and carrying tasks. Sex differences in strength and fatigability are established for many limb muscles and back extensor muscles, but it is ...
Deering, Rita, Hunter, Sandra K., Neumann, Donald A., Pashibin, Tatyana, Senefeld, Jonathon   +4 more
core   +2 more sources