Results 81 to 90 of about 1,069,554 (324)

The Effects of Multiple Acute Turkesterone Doses on Indirect Measures of Hypertrophy and Metabolic Measures: A Preliminary Investigation

Muscles
Turkesterone is a naturally occurring plant steroid touted for its medicinal, pharmacological, and biological properties with no reported adverse side effects compared with traditional anabolic androgenic steroids (AAS).
Dillon R. Harris, Tomas Chapman-Lopez, Steven B. Machek, Jeffery S. Forsse, Tracey Sulak, Leslee K. Funderburk   +5 more
doaj   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

Reliability of Sensorimotor Control Tests in Individuals with Adolescent Idiopathic Scoliosis

Muscles
Background: The presence of sensorimotor control deficits in adolescent idiopathic scoliosis compared to typically developed adolescents is supported by the literature but lacks reliability studies for assessment in this population.
Alexandros Kastrinis, Nikolaos Strimpakos, George A. Koumantakis, Dionysios Tzatzaliaris, Marianna Oikonomaki, Evangelos Theodosopoulos, Evangelia Skaftourou, Maria Tsekoura, Asimakis K. Kanellopoulos, Eleni Nomikou, Zacharias Dimitriadis   +10 more
doaj   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

FEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu, Qing Dai, Jing Leng, Lin Fang, Jing‐Jing Ma, Rui Chen, Che Chen, Peng‐Fei Ran, Wen‐Wen Zhou, Chang Liu, Huang‐Fei Yu   +10 more
wiley   +1 more source

Noninvasive Assessments of Mitochondrial Capacity in People with Mitochondrial Myopathies

Muscles
People affected by mitochondrial myopathies (MITOs) are thought to have impaired skeletal muscle oxygenation. The aims of this study were to measure skeletal muscle mitochondrial capacity in MITO participants and able-bodied (AB) participants and ...
Kevin K. McCully, Hannah M. Bossie, Fran D. Kendall   +2 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Correlation Between Maximal Eccentric and Isometric Multi-Joint Lower-Extremity Strength and Vertical Jumping Performance in Young Adults

Muscles
Maximal eccentric (MES) and isometric (MIS) muscle strength may enhance vertical jump performance by facilitating preloading and reducing energy loss during the eccentric (ECC) phase of the stretch-shortening cycle (SSC).
Joonsun Park, Cassidy Weeks, Brennan J. Thompson, Talin Louder   +3 more
doaj   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Validity and Reliability of a Smartphone Application Versus 2D Software for Joint Range of Motion Measurement: A Cross-Sectional Validation Study

Muscles
The assessment of joint ranges is an essential component of the physical examination, enabling monitoring and follow-up. Additionally, it is a key component of muscle mobility assessment.
Inès Martins, Misha Gunot, Amândio Dias   +2 more
doaj   +1 more source

The Influence of Knee Proprioception and Strength on Lower-Limb Functional Symmetry in Healthy Adults

Muscles
This study examined the association between knee proprioception, strength, and functional symmetry in healthy individuals using isokinetic strength tests, proprioception assessments, and hop tests. Twenty young, healthy adults (mean age 26.5 ± 4.1 years,
Joffrey Drigny, Marine Rolland, Antoine Gauthier   +2 more
doaj   +1 more source