Results 21 to 30 of about 380,196 (292)

Circulating microRNA expression signatures accurately discriminate myalgic encephalomyelitis from fibromyalgia and comorbid conditions

open access: yesScientific Reports, 2023
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and fibromyalgia (FM) are two chronic complex diseases with overlapping symptoms affecting multiple systems and organs over time.
Evguenia Nepotchatykh   +10 more
doaj   +1 more source

Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

open access: yesMilitary Medical Research, 2023
Degenerative musculoskeletal diseases are structural and functional failures of the musculoskeletal system, including osteoarthritis, osteoporosis, intervertebral disc degeneration (IVDD), and sarcopenia.
Ze-Qin Wen   +5 more
doaj   +1 more source

Value of MRI and ultrasound for prediction of therapeutic response and erosive progression in patients with early rheumatoid arthritis managed by an aggressive treat-to-target strategy

open access: yesRMD Open, 2021
Objectives To investigate if inflammation detected by MRI or ultrasound at rheumatoid arthritis (RA) onset is predictive of erosive progression or poor response to methotrexate monotherapy, and to investigate if subclinical inflammation in remission is ...
  +20 more
doaj   +1 more source

Optimal treatment strategies for musculoskeletal diseases [PDF]

open access: yes, 2013
This paper presents a model which aims to find an optimal treatment time for patients with musculoskeletal diseases. The stochastic dynamic programming model presented is based on minimizing expected costs given a stochastic processes for cure with ...
Haugen, Kjetil K.
core   +1 more source

MRI-guided focused ultrasound surgery in musculoskeletal diseases: the hot topics [PDF]

open access: yes, 2015
MRI-guided focused ultrasound surgery (MRgFUS) is a minimally invasive treatment guided by the most sophisticated imaging tool available in today's clinical practice.
Albisinni, Ugo   +6 more
core   +1 more source

Incidence of Unrecognized Incidental Durotomy during Surgery for Malignant Spinal Tumor

open access: yesSpine Surgery and Related Research, 2020
Introduction: Cerebral spinal fluid leak from durotomy is a well-known risk with spinal surgeries. The aim of this study is to identify the incidence of unrecognized incidental durotomy during posterior surgery for spinal metastases and its risk factors.
Takuma Koyama   +6 more
doaj   +1 more source

Angiogenic T Cells: Potential Biomarkers for the Early Diagnosis of Interstitial Lung Disease in Autoimmune Diseases?

open access: yesBiomedicines, 2022
(1) Background: We explored, for the first time, the contribution of angiogenic T cells (TAng) in interstitial lung disease associated to autoimmune disease (AD-ILD+) as potential biomarkers of the disease, evaluating their role in the underlying ...
Verónica Pulito-Cueto   +15 more
doaj   +1 more source

Appropriateness and efficacy of Spa therapy for musculoskeletal disorders. A Delphi method consensus initiative among experts in Italy. [PDF]

open access: yes, 2017
OBJECTIVE: The aim of the study was to identify the main aspects concerning appropriateness and efficacy of Spa therapy for musculoskeletal pathologies. METHODS: A committee of 8 experts from Italian universities, public hospitals, territorial services,
BERNETTI, ANDREA   +12 more
core   +1 more source

Lived experiences of informal caregivers of people with chronic musculoskeletal pain: a systematic review and meta-ethnography [PDF]

open access: yes, 2021
BACKGROUND: People with chronic pain often seek support from friends and family for everyday tasks. These individuals are termed informal caregivers. There remains uncertainty regarding the lived experiences of these people who care for individuals with ...
Bowlby J.   +6 more
core   +1 more source

Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units

open access: yesCell Reports, 2019
Summary: Age-related loss of skeletal muscle innervation by motor neurons leads to impaired neuromuscular function and is a well-established clinical phenomenon. However, the underlying pathogenesis remains unclear. Studying mice, we find that the number
Elisa Giorgetti   +18 more
doaj   +1 more source

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