Results 151 to 160 of about 446,114 (349)

Chapter 4: Disabilities Related to the Musculoskeletal System: Physical Evaluation Board Data

, 1999
Paul J. Amoroso, Michelle L. Canham
openalex   +1 more source

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

Advanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv, Xiang Zhao, Songsong Teng, Xinmeng Jin, Ying Zhou, Yueyang Sun, Hao Pei, Zuoqin Yan, Chunhui Ma   +8 more
wiley   +1 more source

Editorial: Nonlinear dynamics and complex patterns in the human musculoskeletal system and movement. [PDF]

Front Bioeng Biotechnol, 2023
Jan YK, Lin CF, Liao F, Singh NB.
europepmc   +1 more source

Tenascin expression in normal and pathological conditions of the musculoskeletal system

, 1996
Tian-Fang Li, Yrjö T. Konttinen, Jingwen Xu, Shinji Imai, Marco Matucci‐Cerinic, Arnoldas Čeponis, Seppo Santavirta, Ismo Virtanen   +7 more
openalex   +2 more sources

Brachyury‐Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment

Advanced Science, EarlyView.
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong, Wenxiao Shi, Xingzhu Liu, Hang Yu, Yinghui Wu, Yanzhang Xia, Caichun Yue, Chongkai Yang, Cong Shen, Renjun Pei, Tianwen Xin, Hailong Pei, Jun Shen   +12 more
wiley   +1 more source

Editorial: Impact and consequences of COVID-19 on the musculoskeletal system. [PDF]

Front Med (Lausanne), 2023
Toussirot E, Maglio M, Fini M, Salamanna F.   +3 more
europepmc   +1 more source

Imaging of Systemic Rheumatoid Diseases Involving the Musculoskeletal System (CME-Questionaire) [PDF]

, 2004
F. Kainberger
openalex   +1 more source

Human iPSCs Derived MSCs‐Secreted Exosomes Modulate Senescent Nucleus Pulposus Cells Induced Macrophage Polarization via Metabolic Reprogramming to Mitigate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Senescent nucleus pulposus cells drive inflammatory M1 macrophage polarization, exacerbating intervertebral disc degeneration (IDD). Conversely, M1 macrophages accelerate NP cell senescence, creating a vicious cycle. iPSCs‐derived mesenchymal stem cell (iMSCs) exosomes break this loop by delivering miR‐100‐5p to suppress mTORC1/glycolysis in ...
Qian Xiang, Jiawen Zhan, Shuo Tian, Yongzhao Zhao, Zhenquan Wu, Jialiang Lin, Longting Chen, Longjie Wang, Shuai Jiang, Zhuoran Sun, Weishi Li   +10 more
wiley   +1 more source

Highlights in Pathophysiology of the Musculoskeletal System. [PDF]

Int J Mol Sci, 2023
Barone R, Szychlinska MA.
europepmc   +1 more source

Dynamic Bonds Reinforced Polyamide Elastomer for Biomedical Orthosis

Advanced Science, EarlyView.
A dynamic bonds (DBs) reinforced shape memory polyamide elastomer is developed using reactive extrusion. Dynamic covalent networks enhance interlayer adhesion in 4D‐printed objects by utilizing the combined effects of multiple DBs, reducing mechanical anisotropy and improving the mechanical and shape memory properties.
Zhen Li, Peiyao Yan, Hao Wang, Yuancheng Zhang, Junhua Kong, Wei Zhao, Xin Li, Xiaomeng Zhang, Zhe Cui, Peng Fu, Xinchang Pang, Minying Liu, Chaobin He   +12 more
wiley   +1 more source