Results 21 to 30 of about 470,712 (310)

Purification and interactions of the MucA’ and MucB proteins constituting the DNA polymerase RI

Genes and Environment, 2019
Background The MucA’ and MucB proteins comprise the core of DNA polymerase RI which is a strong mutator utilized in mutagenicity assays such as the standard Ames test. A close relative DNA polymerase V, composed of the homologous UmuD’ and UmuC proteins,
Petr Grúz, Kei-ichi Sugiyama, Masamitsu Honma, Takehiko Nohmi   +3 more
doaj   +1 more source

ENU mouse mutagenesis: Generation of mouse mutants with aberrant plasma IgE levels [PDF]

, 2001
peer reviewedBACKGROUND: The ENU Mouse Mutagenesis Project aims at a large-scale, systematic production of mouse mutants using the alkylating agent ethyl-nitrosourea (ENU).
Wolf, A., Behrendt, Heidrun, Alessandrini, Francesca, Behrend, H., Ring, J., Wolf, Alexander, Ring, Johannes, Jakob, T., Jakob, Thilo, Alessandrini, F., Wolf, Eckhard, Hrabé de Angelis, Martin, Wolf, E., Balling, R., Balling, Rudolf, Alessandrini, F. ; Jakob, T. ; Wolf, A. ; Wolf, E. ; Balling, R. ; Hrabé de Angelis, M. ; Ring, J. ; Behrend, H., Alessandrini, Francesca;Jakob, Thilo;Wolf, Alexander;Wolf, Eckhard;Balling, Rudolf;de Angelis, Martin Hrabe;Ring, Johannes;Behrendt, Heidrun, Hrabě de Angelis, M.   +17 more
core   +1 more source

Antigenotoxic Effect of Ascorbic Acid and Resveratrol in Erythrocytes of Ambystoma mexicanum, Oreochromis niloticus and Human Lymphocytes Exposed to Glyphosate

Current Issues in Molecular Biology, 2022
Glyphosate is a controversial herbicide. Its genotoxicity and presence in various ecosystems have been reported. The use of ascorbic acid and resveratrol could protect different organisms from glyphosate-induced genetic damage.
Carlos Alvarez-Moya, Alexis Gerardo Sámano-León, Mónica Reynoso-Silva, Rafael Ramírez-Velasco, Mario Alberto Ruiz-López, Alma Rosa Villalobos-Arámbula   +5 more
doaj   +1 more source

Implementation of transposon mutagenesis in Bifidobacterium [PDF]

, 2019
Random transposon mutagenesis allows for relatively rapid, genome-wide surveys to detect genes involved in functional traits, by performing screens of mutant libraries. This approach has been widely applied to identify genes responsible for activities of
van Sinderen, Douwe, Lorena Ruiz, Ruiz, Lorena, Douwe van Sinderen   +3 more
core   +1 more source

UV- and MMS-induced mutagenesis of lambdaO(am)8 phage under nonpermissive conditions for phage DNA replication. [PDF]

, 2003
Mutagenesis in Escherichia coli, a subject of many years of study is considered to be related to DNA replication. DNA lesions nonrepaired by the error-free nucleotide excision repair (NER), base excision repair (BER) and recombination repair (RR), stop ...
Felczak, Magdalena, Krwawicz, Joanna, Pietrzykowska, Irena, Czajkowska, Anna   +3 more
core   +1 more source

Identification of Single Nucleotide Polymorphism in TaSBEIII and Development of KASP Marker Associated With Grain Weight in Wheat

Frontiers in Genetics, 2021
Manipulation of genes involved in starch synthesis could significantly affect wheat grain weight and yield. The starch-branching enzyme (SBE) catalyzes the formation of branch points by cleaving the α-1,4 linkage in polyglucans and reattaching the chain ...
Ahsan Irshad, Huijun Guo, Shoaib Ur Rehman, Xueqing Wang, Jiayu Gu, Hongchun Xiong, Yongdun Xie, Linshu Zhao, Shirong Zhao, Chaojie Wang, Luxiang Liu   +10 more
doaj   +1 more source

Evaluation of oxidative stress responses in human circulating blood cells after imatinib mesylate treatment – Implications to its mechanism of action

Saudi Pharmaceutical Journal, 2019
Imatinib mesylate (IM) is the first developed protein kinase inhibitor and recently it has topped consumption rates among targeted and total anticancer drugs.
Goran Gajski, Marko Gerić, Ana-Marija Domijan, Ivana Golubović, Vera Garaj-Vrhovac   +4 more
doaj   +1 more source

Current perspectives on mechanisms of ribonucleotide incorporation and processing in mammalian DNA

Genes and Environment, 2019
Ribonucleotides, which are RNA precursors, are often incorporated into DNA during replication. Although embedded ribonucleotides in the genome are efficiently removed by canonical ribonucleotide excision repair (RER), inactivation of RER causes genomic ...
Akira Sassa, Manabu Yasui, Masamitsu Honma   +2 more
doaj   +1 more source

Identification of the vernalization gene VRN-B1 responsible for heading date variation by QTL mapping using a RIL population in wheat

BMC Plant Biology, 2020
Background Heading time is one of the most important agronomic traits in wheat, as it largely affects both adaptation to different agro-ecological conditions and yield potential.
Yuting Li, Hongchun Xiong, Huijun Guo, Chunyun Zhou, Yongdun Xie, Linshu Zhao, Jiayu Gu, Shirong Zhao, Yuping Ding, Luxiang Liu   +9 more
doaj   +1 more source

Development of a simple multiple mutation detection system using seed-coat flavonoid pigments in irradiated Arabidopsis M1 plants

Scientific Reports, 2022
Ionizing radiation induces genetic variations in plants, which makes it useful for plant breeding. A theory that the induced mutations occur randomly in the genome has long been accepted, but is now controversial.
Satoshi Kitamura, Shoya Hirata, Katsuya Satoh, Rie Inamura, Issay Narumi, Yutaka Oono   +5 more
doaj   +1 more source