Results 161 to 170 of about 13,277,354 (332)

Mutagenic Potential Evaluation of the Water of a River That Receives Tannery Effluent Using the Allium cepa Test System

, 2004
Sílvia Tamie Matsumoto, Maria Aparecida Marin‐Morales   +1 more
openalex   +2 more sources

Resolution of historically discordant Ames test negative/rodent carcinogenicity positive N-nitrosamines using a sensitive, OECD-aligned design. [PDF]

Mutagenesis
Thomas DN, Wills JW, Burman M, Williams AN, Harte DSG, Buckley RA, Urquhart MW, Bretonnet AS, Jeffries B, White AT, Harvey JS, Howe JR, Lynch AM.   +12 more
europepmc   +1 more source

RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA

Cell Proliferation, EarlyView.
Targeting RBM39 attenuates BER via destabilising OGG1 mRNA and potentiates KBrO3‐induced oxidative stress in HCC. Our study represents a valuable treatment strategy combining indisulam and an oxidative stress inducer in HCC. ABSTRACT Targeting base excision repair (BER) has been an attractive strategy in cancer therapeutics.
Hongda An, Anliang Xia, Siyuan Liu, Dongjun Luo, Longpo Geng, Binghua Li, Beicheng Sun, Zhu Xu   +7 more
wiley   +1 more source

New Synthetic Opioids: What Do We Know About the Mutagenicity of Brorphine and Its Analogues? [PDF]

Int J Mol Sci
Lenzi M, Gasperini S, Bilel S, Corli G, Rombolà F, Hrelia P, Marti M.   +6 more
europepmc   +1 more source

Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development

The FEBS Journal, EarlyView.
Three skeletal muscle diseases are linked to HMGCR, a key enzyme in cholesterol synthesis. These diseases include a muscular dystrophy associated with pathogenic variants in the HMGCR gene, statin‐associated myopathy, and autoimmune anti‐HMGCR myopathy.
Mekala Gunasekaran, Hannah R. Littel, Natalya M. Wells, Johnnie Turner, Gloriana Campos, Sree Venigalla, Elicia A. Estrella, Partha S. Ghosh, Audrey L. Daugherty, Seth A. Stafki, Louis M. Kunkel, A. Reghan Foley, Sandra Donkervoort, Carsten G. Bönnemann, Laura Toledo‐Bravo de Laguna, Andres Nascimento, Daniel Natera‐de Benito, Isabelle Draper, Christine C. Bruels, Christina A. Pacak, Peter B. Kang   +20 more
wiley   +1 more source

Biosafety and Protective Effects of Tyrosol from Olea europaea L. in Gingivitis: In Vitro and in Vivo Studies

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To evaluate tyrosol's biosafety in cytotoxicity, genotoxicity, mutagenicity, and acute toxicity studies in an experimental gingivitis model. Material and Methods: Tyrosol was extracted from a freeze-dried and ultra-processed extract of olive ...
Adriano Costa Ramos, Maria Cecília Freire de Melo, Amanda Ketelly Melo de Lima, Talita Giselly Souza, Andressa Kelly Alves Ferreira, Thuanny Silva de Macêdo, Arnaldo de França Caldas Júnior, Adriana Maria da Silva Telles, Gustavo Pina Godoy   +8 more
doaj  

Effects of Monascus Colorants on the Mutagenicity of Nitrite-Treated 1-Aminopyrene Using Ames Test(ผล ของส ีท ี่ได ้จ าก เชื้อ รา Monascus ต่อฤทธก,อ ก ล ายพ ัน ธ ุข อ ง...

, 2005
Kalyarat Kruawan, Kaew Kangsadalampai, Busaba Yongsmith, Thayat Sriyapai   +3 more
openalex   +2 more sources

Structure-mutagenicity relationships on quinoline and indole analogues in the Ames test. [PDF]

Genes Environ
Kurakami M, Hakura A, Sato R, Kawade A, Yamagata T, Koyama N, Kakiuchi D, Asakura S.   +7 more
europepmc   +1 more source

Tracing the evolutionary pathway: on the origin of mitochondria and eukaryogenesis

The FEBS Journal, EarlyView.
This study examines the stepwise transition from archaeal–bacterial associations to the emergence of eukaryotic cells. Metabolic cooperation and endosymbiosis fostered ecological and genetic integration, with extensive gene transfer reshaping host biology.
J. Ernesto Bravo‐Arévalo
wiley   +1 more source

Development of Saccharomyces cerevisiae Y486–based biosensor carrying both CPR-CYP3A4 and DIN7-GFP constructs for mutagenicity testing of procarcinogens

, 2021
Nguyễn Thị Thu Huyền, Van Ngoc Bui
openalex   +2 more sources