Results 151 to 160 of about 10,959 (312)

Practical aspects of mutagenicity testing. [PDF]

Environmental Health Perspectives, 1973
openaire   +2 more sources

A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies

Addiction, EarlyView.
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr, Ana Lucia Espinosa Dice, Gerhard E. Gmel Sr., Ahmed S. Hassan, Kevin D. Shield, Jürgen Rehm   +5 more
wiley   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Assessment of mutagenic potential of puberulic acid contaminated in red yeast rice (beni-koji) health food supplements. [PDF]

Mutagenesis
Sugiyama KI, Furuhama A, Horibata K, Tsuda M, Izawa K, Tsuji G, Demizu Y, Matsushita K, Toyoda T, Hirabayashi Y, Saito Y, Honma M.   +11 more
europepmc   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Food science and techniques. Reports of the Scientific Committee for Food (42nd series) [PDF]

, 1999

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On the replacement of in vivo tests on germ cell mutagenicity and fertility impairment

, 2005
In contrast to drugs, industrial chemicals are not intended to be uptaken directly by humans. They mainly serve as intermediates for preparations and products.
Seiler,A., Liebsch,M., Spielmann,H., Genschow,E., Klemm,M., Vogel,R.   +5 more
core  

Adjusting the Preincubation Conditions to Enhance the Ames Test for Detecting the Mutagenicity of N-Nitrosamines. [PDF]

Environ Mol Mutagen
Bishop ME, Sims AM, Guerrero SK, Mitchell K, Mei N, Xu H, Kruhlak NL, King ST, Dorsam RT, Atrakchi AH, McGovern TJ, Heflich RH.   +11 more
europepmc   +1 more source

Spontaneous miscarriage after intracytoplasmic sperm injection with frozen sperm of patients with testicular germ cell tumour

BJU International, EarlyView.
Objective To clarify the impact of chromosomal aberrations on the offspring of patients with testicular germ cell tumour (TGCT) by evaluating the outcomes of intracytoplasmic sperm injection (ICSI). Patients and Methods Under the ethical review of Yokohama City University, 12 patients with TGCT and 25 with non‐TGCT cancer who had cryopreserved sperm ...
Haru Hamada, Akifumi Ijuin, Tomonari Hayama, Naoki Tsuchiya, Sumiko Sueyoshi, Misaki Toda, Ai Miyakoshi, Mayuko Kurumizaka, Marina Saito, Yuki Oike, Hiroe Ueno, Shinnosuke Kuroda, Kazumi Takeshima, Teppei Takeshima, Shin Saito, Ryoko Asano, Taichi Mizushima, Yasushi Yumura, Hideya Sakakibara, Etsuko Miyagi, Miki Tanoshima, Mariko Murase   +21 more
wiley   +1 more source

First report on certain additives used in the manufacture of plastic materials intended to come into contact with foodstuffs (Opinions expressed until 3 May 1992). Reports of the Scientific Committee for Food. Thirty-third series [PDF]

, 1995

core