On the potential genotoxic/mutagenic effects of peroxide-treatment on organic fractions of thermal-mineral waters. [PDF]
Varga C.
europepmc +1 more source
In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.
Jakob Nückles +15 more
wiley +1 more source
Practical aspects of mutagenicity testing. [PDF]
openaire +2 more sources
LMTK2 Inhibits Metastasis of Colon Cancer Cells Through p38 MAPK
LMTK2 suppresses colon cancer metastasis by acting as a kinase‐independent scaffold that directly binds p38, blocking its interaction with MKK3/6 and subsequent phosphorylation, thereby inhibiting the downstream pro‐metastatic gene program. ABSTRACT Metastasis is the leading cause of death in patients with colon cancer. Although Lemur tyrosine kinase 2
Jie Lun +6 more
wiley +1 more source
Decoupling of Bypass Efficiency and Mutagenicity of the 2-Acetylaminofluorene C8-Guanine Adduct by DNA Sequence Context. [PDF]
Chen YT +5 more
europepmc +1 more source
Abstract This study investigates the electrochemical decolorization of waste acid dye baths and evaluates their potential reuse in subsequent textile dyeing processes. Four different anode materials (iron, aluminum, stainless steel and graphite) were examined to optimize color removal efficiency and assess the influence of electrochemically generated ...
Yunus Emre Kayserili, Asım Davulcu
wiley +1 more source
Assessment of mutagenic potential of puberulic acid contaminated in red yeast rice (beni-koji) health food supplements. [PDF]
Sugiyama KI +11 more
europepmc +1 more source
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar +5 more
wiley +1 more source
From QSAR to deep learning: an interpretable comprehensive pipeline with a read-across approach for mutagenicity prediction <i>via</i> the Enalos Cloud Platform. [PDF]
Varsou DD +9 more
europepmc +1 more source
Differential Mutagenic Response of Rat Liver and Lung to Nicotine-Derived Nitrosamine Ketone (NNK). [PDF]
Jolly RA +5 more
europepmc +1 more source

