Results 161 to 170 of about 10,959 (312)

Complex versus simple <i>N</i>-nitrosamines: Comprehensive genotoxicity and in silico carcinogenicity assessment toward future testing paradigms. [PDF]

Sci Adv
Sun X, Schuler M, Zhang S, Kostal J, Cheung JR, Kenyon M, Watt E, Dobo K.   +7 more
europepmc   +1 more source

Afatinib Overcomes Osimertinib Resistance via Egfr V804F Mutation in a Syngeneic Egfr‐Mutant Lung Cancer Mouse Model

Cancer Science, EarlyView.
Using an immunocompetent mouse model of Egfr Ex19del‐driven lung cancer, we found that osimertinib‐resistant tumors acquired Egfr V804F, the murine counterpart of human EGFR V802F. Afatinib, but not osimertinib, suppressed phosphorylation of EGFR and overcame V804F‐mediated resistance, providing a preclinical rationale for biomarker‐guided therapy ...
Takaaki Tanaka, Masato Fujitani, Masataka Taoka, Iwao Shimomura, Sachi Okawa, Shunta Mori, Tadahiro Kuribayashi, Jun Nishimura, Tomoka Nishimura, Ayako Morita, Naofumi Hara, Kiichiro Ninomiya, Go Makimoto, Hisao Higo, Kammei Rai, Eiki Ichihara, Shuta Tomida, Katsuyuki Hotta, Yosuke Togashi, Yoshinobu Maeda, Katsuyuki Kiura, Ryohei Katayama, Kadoaki Ohashi   +22 more
wiley   +1 more source

Genotoxic hazards in the rubber industry : application of short-term tests in work environment analyses

, 1984
Excess mortality from a number of different types of cancer has been associated with work in the rubber industry. The aim of the present study - using short-term tests for mutagenicity - was to identify potentially hazardous additives and process fumes ...
Rannug, Agneta,
core  

Preliminary Genotoxicity Assessment of Calcium Phosphate Cement Incorporated with Palm Tocotrienol Using Bacterial Reverse Mutation Assay. [PDF]

Biomedicines
Wong SK, Md Dali SS, Chin KY, Ahmad F, Ariffin AH, Fauzi FM, Mahmud MZ, Ahmad Sabri IH.   +7 more
europepmc   +1 more source

Occurrence and Washout of Health‐Hazardous Chemicals in Children's Clothing

Contact Dermatitis, EarlyView.
A survey of 60 children's garments from the Swedish market showed a varying, often highly complex chemical content. The highest levels were generally found in synthetic materials and the lowest in light‐coloured cotton. Further, the washout effect by laundry and sweat migration of textile chemicals was investigated.
Awat Dostberg, Tim Åström, Ioannis Sadiktsis, Conny Östman, Ulrika Nilsson   +4 more
wiley   +1 more source

Synthesis, Mutagenicity, and Metabolism of Substituted 4,4'-Aminoakoxyazobenzene dyes

, 2009
This study is an extension of previous work in our laboratories pertaining to the effects of substituents on the mutagenicity of aminoazobenzene-based dyes.
Jeong, Euigyung
core  

Human aldo-keto reductases (AKR1C1-AKR1C3) increase the mutagenicity of environmental nitroarenes in the mammalian HPRT forward gene mutagenicity assay. [PDF]

Mutat Res Genet Toxicol Environ Mutagen
Su AL, Marques CF, El-Bayoumy K, Penning TM.   +3 more
europepmc   +1 more source

Electrochemical decolorization of acid dye baths and their reuse potential in subsequent textile dyeing processes

Coloration Technology, EarlyView.
Abstract This study investigates the electrochemical decolorization of waste acid dye baths and evaluates their potential reuse in subsequent textile dyeing processes. Four different anode materials (iron, aluminum, stainless steel and graphite) were examined to optimize color removal efficiency and assess the influence of electrochemically generated ...
Yunus Emre Kayserili, Asım Davulcu
wiley   +1 more source

Therapeutic potential of Brazilian medicinal plants and their metabolites. [PDF]

Genet Mol Biol
Serpeloni JM, Santos FVD, Tuttis K, Cólus IMS.   +3 more
europepmc   +1 more source

High-Throughput Testing for Unknown Mutagens and Cytotoxica via Duplex Planar Ames-Cytotoxicity Bioassay Including Metabolic S9 Activation. [PDF]

Anal Chem
Schmidtmann K, Kayser AC, Morlock GE.
europepmc   +1 more source