Results 161 to 170 of about 2,851,396 (315)

PTEN homozygous deletion is a negative prognostic factor in tumor treating fields‐treated glioblastoma, IDH wildtype patients

open access: yesBrain Pathology, EarlyView.
In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.
Jakob Nückles   +15 more
wiley   +1 more source

LMTK2 Inhibits Metastasis of Colon Cancer Cells Through p38 MAPK

open access: yesCancer Science, EarlyView.
LMTK2 suppresses colon cancer metastasis by acting as a kinase‐independent scaffold that directly binds p38, blocking its interaction with MKK3/6 and subsequent phosphorylation, thereby inhibiting the downstream pro‐metastatic gene program. ABSTRACT Metastasis is the leading cause of death in patients with colon cancer. Although Lemur tyrosine kinase 2
Jie Lun   +6 more
wiley   +1 more source

Electrochemical decolorization of acid dye baths and their reuse potential in subsequent textile dyeing processes

open access: yesColoration Technology, EarlyView.
Abstract This study investigates the electrochemical decolorization of waste acid dye baths and evaluates their potential reuse in subsequent textile dyeing processes. Four different anode materials (iron, aluminum, stainless steel and graphite) were examined to optimize color removal efficiency and assess the influence of electrochemically generated ...
Yunus Emre Kayserili, Asım Davulcu
wiley   +1 more source

Assessment of mutagenic potential of puberulic acid contaminated in red yeast rice (beni-koji) health food supplements. [PDF]

open access: yesMutagenesis
Sugiyama KI   +11 more
europepmc   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

open access: yesCell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar   +5 more
wiley   +1 more source

From QSAR to deep learning: an interpretable comprehensive pipeline with a read-across approach for mutagenicity prediction <i>via</i> the Enalos Cloud Platform. [PDF]

open access: yesRSC Adv
Varsou DD   +9 more
europepmc   +1 more source

Differential Mutagenic Response of Rat Liver and Lung to Nicotine-Derived Nitrosamine Ketone (NNK). [PDF]

open access: yesChem Res Toxicol
Jolly RA   +5 more
europepmc   +1 more source

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