Results 131 to 140 of about 15,527,587 (352)

In vitro cytotoxicity and genotoxicity assessment of methanolic extracts of vanillas from Brazilian biodiversity with commercial potential

open access: yesToxicology Reports
The Vanilla genus is crucial for global production in food, perfume, and pharmaceutical industries. However, exploitation threatens some species, leading to extinction.
Natália Gonçalves Ribeiro Araujo   +4 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler   +5 more
wiley   +1 more source

樟树籽仁油的遗传毒性评价

open access: yesZhongguo youzhi
为评价樟树籽仁油的食用安全性,通过细菌回复突变试验、体外哺乳类细胞TK基因突变试验及哺乳动物红细胞微核试验探究樟树籽仁油的致突变和潜在致癌作用。结果表明:樟树籽仁油对组氨酸缺陷型鼠伤寒沙门氏菌TA1535、TA97、TA98、TA100、TA102均无致突变作用;樟树籽仁油未抑制L5178Y小鼠淋巴瘤细胞的生长,对体外哺乳类细胞TK基因无致突变作用;樟树籽仁油未导致小鼠细胞微核率上升,对哺乳动物红细胞无致突变作用,无遗传毒性。综上,樟树籽仁油无细胞致突变和潜在致癌作用,没有遗传毒性,具有一定的食用安全性。
彭婷1,2,3,梁丽军4,曾哲灵1,2,5,张淑虹1,5,鄢祥辉1,2,6,夏佳恒1,2,5,余平1,2,5, 万冬满1,2,3,文学方7,8 PENG Ting1,2,3, LIANG Lijun4, ZENG Zheling1,2,5, ZHANG Shuhong1,5, YAN Xianghui1,2,6, XIA Jiaheng1,2,5, YU Ping1,2,5, WAN Dongman1,2,3, WEN Xuefang7,8
doaj   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan   +2 more
wiley   +1 more source

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves   +3 more
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo   +10 more
wiley   +1 more source

Alternative Approaches Can Reduce the Use of Test Animals under REACH. [PDF]

open access: yes, 2004
not availableJRC.I-Institute for Health and Consumer Protection ...
DE BRUIJN J.   +3 more
core  

The Employment of Hydrogen Peroxide in Water Disinfection Poses a Threat to Aquatic Ecosystems Because of Its Toxicity to Nontarget Organisms

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Hydrogen peroxide is widely used in water and wastewater treatment, particularly in advanced oxidation processes that aid in the degradation of compounds and microbial disinfection. Despite concerns about potential environmental contamination, its impact on freshwater ecosystems remains inadequately studied.
Letícia Queiroz Almeida   +7 more
wiley   +1 more source

Nanosilica coating for bonding improvements to zirconia

open access: yesInternational Journal of Nanomedicine, 2013
Chen Chen, Gang Chen, Haifeng Xie, Wenyong Dai, Feimin Zhang Institute of Stomatology, Nanjing Medical University, Nanjing, Jiangsu Province, People's Republic of China Abstract: Resin bonding to zirconia cannot be established from standard methods ...
Chen C, Chen G, Xie H, Dai W, Zhang F
doaj  

Genotoxicity assessment of Elaeagnus angustifolia L. fruit extract (senjed) nanocapsule by in vitro and in vivo methods

open access: yesJournal of Medicinal Plants, 2020
Background: Although initial studies on Elaeagnus Angustifolia L. Fruit Extract (Senjed) Nanocapsule showed its efficacy in osteoporosis in rat model as well as its significant role in elevating the serum calcium levels, there is no study on its possible
Negar Zamani   +2 more
doaj  

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