Results 111 to 120 of about 10,959 (312)
Topological structural alerts modulations of mammalian cell mutagenicity for halogenated derivatives
, 2014 Genotoxicity is a key toxicity endpoint for current regulatory requirements regarding new and existing chemicals. However, genotoxicity testing is time-consuming and costly, and involves the use of laboratory animals.
A. Pérez-Garrido (536898) +4 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos +4 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto +7 more
wiley +1 more source
Cytotoxicity and Mutagenicity of Micropollutants in Drinking Water
, 1992 In order to examine whether cytotoxicity test is available as bioassay of water micropollutants, cytotoxicities of 40 chemicals, which have been reported to occur in drinking water, were investigated using 3 different types of cultured cells including HL-
M. Hakoda +7 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan +3 more
wiley +1 more source
Genotoxic assessments of Tigris river surface water with Salmonella mutagenicity and SOS-chromotests
, 2007 Two in vitro tests (Salmonella/microsome mutagenicity test and SOS chromotest), one for bacterial mutagenicity and one for primary DNA damage, were assayed to determine the genotoxic activity of surface water of Tigris river.
Otludil, Birol, Tolan, Veysel
core
Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology
Journal of the Chinese Chemical Society, EarlyView.Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley +1 more source
Revista de Ciências Farmacêuticas Básica e Aplicada, 2012 Bathysa cuspidata (A.St.-Hil.) Hook. is a native tree of the Brazilian Atlantic Forest biome, widely used in Brazilian herbal medicine. Despite its widespread use, there is no report as yet regarding the toxicology of this plant.
Douglas Costa Gontijo +4 more
doaj +2 more sources
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos +11 more
wiley +1 more source
Brazilian Journal of BiologyAlthough the use of medicinal plants or natural products has increased in recent decades all over the world, little information is available on their potential risk to health.
JB. Vilar, PH. Ferri, L. Chen-Chen
doaj +1 more source