Results 121 to 130 of about 10,959 (312)
Journal of Heterocyclic Chemistry, EarlyView.N‐nitrosamine impurities (B, C, E, H, I, J) of timolol maleate are easily synthesized from diethyl malonate and 3,4‐dichloro‐1,2,5‐thiadiazole. Good yields and precise impurity profiling are made possible by the effective technique, which also ensures pharmaceutical safety and strengthens regulatory compliance.
Kottolla Sai Prasad +3 more
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Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai +3 more
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Environmental Effects of Volcanic Volatile Fluxes From Subaerial Large Igneous Provinces
Geophysical Monograph Series, Page 103-116., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Tamsin A. Mather, Anja Schmidt
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Toxicology ReportsThe Vanilla genus is crucial for global production in food, perfume, and pharmaceutical industries. However, exploitation threatens some species, leading to extinction.
Natália Gonçalves Ribeiro Araujo +4 more
doaj +1 more source
Pest Management Science, EarlyView.Hydroxypropyl‐β‐cyclodextrin (HPβCD)–N,N‐diethyl‐meta‐toluamide (DEET) complex extended tick repellency to 168 h. Full protection against Aedes aegypti for 7 h with HPβCD‐DEET. HPβCD reduced DEET release and skin retention significantly. No embryotoxicity observed below 325 mg L−1 in zebrafish model.
Gessyka Rayana Silva Pereira +10 more
wiley +1 more source
, 1979 Four crude oils (Southern Louisiana Crude Petroleum, H Coal Syncrude, Paraho Crude Shale Oil and Geokinetics in situ Shale Oil) which were distilled into four fractions (naphtha, mid-distillate, gas oil and residue) for analysis and biological screening ...
King, C. F. +4 more
core +1 more source
Zhongguo youzhi为评价樟树籽仁油的食用安全性，通过细菌回复突变试验、体外哺乳类细胞TK基因突变试验及哺乳动物红细胞微核试验探究樟树籽仁油的致突变和潜在致癌作用。结果表明：樟树籽仁油对组氨酸缺陷型鼠伤寒沙门氏菌TA1535、TA97、TA98、TA100、TA102均无致突变作用；樟树籽仁油未抑制L5178Y小鼠淋巴瘤细胞的生长，对体外哺乳类细胞TK基因无致突变作用；樟树籽仁油未导致小鼠细胞微核率上升，对哺乳动物红细胞无致突变作用，无遗传毒性。综上，樟树籽仁油无细胞致突变和潜在致癌作用，没有遗传毒性，具有一定的食用安全性。
彭婷1,2,3，梁丽军4，曾哲灵1,2,5，张淑虹1,5，鄢祥辉1,2,6，夏佳恒1,2,5，余平1,2,5， 万冬满1,2,3，文学方7,8 PENG Ting1,2,3, LIANG Lijun4, ZENG Zheling1,2,5, ZHANG Shuhong1,5, YAN Xianghui1,2,6, XIA Jiaheng1,2,5, YU Ping1,2,5, WAN Dongman1,2,3, WEN Xuefang7,8
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Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
Phytotherapy Research, EarlyView.ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
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Phytotherapy Research, EarlyView.ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve +6 more
wiley +1 more source
Feeding safety evaluation of
Siliao yanjiuIn order to evaluate the feeding safety of Astragalus flower, acute oral toxicity tests, Ames mutagenicity tests, mammalian erythrocyte micronucleus tests, mouse spermatogonial chromosomal aberration tests, and a 90-day subacute toxicity test were ...
YU Kan-chao +5 more
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