Results 211 to 220 of about 2,851,396 (315)

Genotoxicity of Carbohydrate Derived Fulvic Acid. [PDF]

Toxicol Rep
Clark SJ, Graz M.
europepmc   +1 more source

A Rapid and Sensitive LC–MS/MS Method for Quantification of NDSRI in Melatonin Drug Product via Controlled In Situ Formation

Biomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT Nitrosamine drug substance–related impurities (NDSRIs) pose a significant safety risk due to their mutagenic and carcinogenic potential, prompting strict regulatory oversight under ICH M7. The propensity for in situ formation of NDSRIs during analytical procedures, particularly in active pharmaceutical ingredients containing reactive amines ...
Jaya Yalamanchili, Ganja Himavathi, Salakolusu Suresh   +2 more
wiley   +1 more source

Effects of electrochemical ageing of lithium-ion battery electrolyte on its in vitro genotoxicity: a special focus on sultones. [PDF]

Arch Toxicol
Muschiol EC, Tölke LS, Lechtenfeld CT, Kuczius T, Winter M, Nowak S, Esselen M.   +6 more
europepmc   +1 more source

Impaired Motor Function in a Zebrafish Stathmin‐2 Knockout Model

Developmental Neurobiology, Volume 86, Issue 4, October 2026.
ABSTRACT Stathmin‐2 (STMN2) is a microtubule‐associated protein that plays a role in the stability of microtubules in axons of the nervous system of animals. In this study, we generated a novel zebrafish STMN2 knockout (KO) model. STMN2 is represented by two genes in the zebrafish genome: stmn2a and stmn2b.
Tyler J. N. Gurberg, Ziyaan A. Harji, Christian J. Rampal, Joséphine Sacy‐Richer, Amy Wang, Esteban C. Rodríguez, Gary A. B. Armstrong   +6 more
wiley   +1 more source

Benchmark Response Values for Error-Corrected Sequencing Mutagenicity Assessment Technologies. [PDF]

Environ Mol Mutagen
Mulugeta S, Marchetti F, Chen G, Chen C, Puglisi R, White PA.   +5 more
europepmc   +1 more source

Natural Preservation of Refrigerated Chicken Meat Using Asphodelus microcarpus Root Extract With Machine‐Learning‐Based Shelf‐Life Prediction

eFood, Volume 7, Issue 5, October 2026.
Multifunctional Preservation & AI Prediction of Chicken Shelf Life. ABSTRACT The demand for natural and multifunctional food preservatives has increased due to growing concerns about the safety and sustainability of synthetic additives. In this study, the ethyl acetate extract of Asphodelus microcarpus roots (AmEA) was evaluated as a preservative ...
Enaam Elsomadi, Boutheina Ben Akacha, Wirginia Kukula‐Koch, Narjes Baazaoui, Monika Michalak, Miroslava Kačániová, Wojciech Koch, Sirine Choura, Mohamed Chamkha, Rania Ben Saad, Stefania Garzoli, Anis Ben Hsouna   +11 more
wiley   +1 more source

Summary of the Safety Assessment Data of the Most Common Organogermanium Food Ingredient, Asaigermanium (Poly-trans-[(2-carboxyethyl)germasesquioxane]). [PDF]

J Food Sci
Doiyama S, Nakamura T.
europepmc   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, Volume 159, Issue 7, Page 1715-1734, 1 October 2026.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

An <i>In vitro</i> assessment of the genotoxic potential of short-, medium-, and long-chain triacylglycerides. [PDF]

Front Toxicol
Schreppler S, Lazouski N, Damen L, Hoffmans R, Petrovic D, Alexander KC.   +5 more
europepmc   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3660-3674, October 2026.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source