Results 281 to 290 of about 13,277,354 (332)

Using Short-Term Mutagenicity Tests for the Evaluation of Genotoxicity of Contaminated Soils

, 1999
The study is aimed at evaluating the genotoxicity of contaminated soils using two bacterial mutagenicity assays — the Ames test and the SOS Chromotest. Initially, attention is directed at the method of extraction of soil samples by organic solvents.
K. Malachová
semanticscholar   +1 more source

Assessment of Mutagenicity Tests

1980
Using the short term tests it is possible to evaluate whether or not chemicals are potential mutagens. The mutagenic hazards for man, however, have to be established by tests on mammals in vivo. Where reproducible mutagenicity findings exist with conclusive tests, consideration of the possible threshold doses, together with benefit/risk equations ...
openaire   +3 more sources

Microorganisms as test systems for mutagenicity [PDF]

Archiv f�r Toxikologie, 1971
The mutagenic activity of different compounds in bacterial mutagenicity test systems has been investigated. The systems used include back-mutations to prototrophy in auxotrophic strains of Serratia marcescens and forward mutations to galactose prototrophy in a phenotypic galactose negative strain of Escherichia coli.
openaire   +2 more sources

Mutagenicity tests with gallic and tannic acid in the Salmonella/mammalian microsome assay.

Journal of Environmental Science and Health. Part B - Pesticides, Food Contaminants, and Agricultural Wastes, 1985
Gallic acid, tannic acid mixture and a purified fraction of tannic acid were evaluated for possible mutagenic activity in three strains of Salmonella typhimurium, TA98, TA100, and TA1535.
K. Rashid, I. Baldwin, J. Babish, J. Schultz, R. Mumma   +4 more
semanticscholar   +1 more source

Mutagen Testing with Maize

1985
The wx locus assay in maize pollen grains may be conducted using one of two chronic treatment regimens and under in situ conditions. Solutions of a test chemical can be applied to the soil of plants grown in pots or to the nutrient medium of plants grown under hydroponic culture. Under in situ conditions, test plots may be constructed in the field, and
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Testing Chemicals for Mutagenicity in a Mammal

Nature, 1966
WHILE admitting that mammals would be preferable to diptera for testing newly introduced drugs for possible genetic (that is, mutagenic) effects, Prof. Luning1 argues that tests with mice would be expensive and time consuming and therefore advocates the use of Drosophila larvae grown on medium containing the drug, which are then tested for chromosome ...
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Use of four short-term tests to evaluate the mutagenicity of municipal water.

Journal of Toxicology and Environmental Health, Part A, 1982
Some ways in which four short-term tests may be used to evaluate the mutagenicity of drinking water were explored by testing raw and treated water from Lake Bloomington, which serves the town of Bloomington, Illinois (population, 44,000).
D. DeMarini, M. Plewa, H. Brockman
semanticscholar   +1 more source

Mutagenicity testing with eukaryotic microorganisms

Archives of Toxicology, 1980
The different genetic end-points which can be tested to detect genotoxicity of chemicals in fungi and especially in the yeast Saccharomyces cerevisiae are described. They include reversion and forward mutation, mitochondrial deletions and point mutations, mitotic or meiotic intra- and intergenic recombination, chromosomal non-disjunction and aneuploidy.
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Mutagenicity of chili extract and capsaicin in short-term tests.

Environmental Mutagenesis, 1985
Vanillin, capsaicin and chili extracts were tested for mutagenicity in Salmonella typhimurium histidine-deficient tester strains TA 98, TA 100, TA 1535, TA 1537, and TA 1538.
M. Nagabhushan, S. Bhide
semanticscholar   +1 more source

Extrapolation of Mutagenicity Testing to the Human

1982
Agricultural genetic toxicology is typical of the challenging problems now being encountered in the rapidly growing field of environmental mutagenesis. Both fields involve a rich diversity of important chemicals, some already known mutagens, a few known carcinogens; both have some hints of human toxicity, but by and large no concrete human data; and ...
openaire   +3 more sources