Results 291 to 300 of about 13,277,354 (332)

Mutagenicity research and testing in Sweden

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1975
A survey is given of Swedish legislation for control of chemicals in the environment. Although no direct legal requirements for mutagenicity testing of chemicals exist at present in Sweden, such requirements can be enforced within the existing laws. Testing and research in chemical mutagenicity are especially performed at the Environmental Toxicology ...
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REVISED METHODS FOR THE SALMONELLA MUTAGENICITY TEST

Mutation Research/Environmental Mutagenesis and Related Subjects, 1983
The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al., 1975b). The present paper is a revision of the methods. Two new tester strains, a frameshift strain (TA97) and a strain carrying an ochre mutation on a multicopy plasmid (TA102), are added to the standard tester set.
Bruce N. Ames, Dorothy M. Maron
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Mutagen Testing with the Soybean Assay

1985
The soybean (Glycine max) system tests for induction of somatic mosaicism on the leaves. This mosaicism results from genetic changes induced by the agent in question in one or more cells which are rapidly dividing. Any type of mosaicism which results in a phenotypically distinct marker can be used.
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A combined testing protocol approach for mutagenicity testing

Mutation Research/Environmental Mutagenesis and Related Subjects, 1979
The antischistosomal agent, hycanthone methanesulfonate (HMS), was employed to illustrate the utility of carrying out several mutagenicity tests in a single concurrent animal experiment. Several commonly used procedures that were successfully integrated into a multiple testing protocol included (1) metaphase analysis in bone marrow, (2) micronucleus ...
Thomas H. Connor, Marvin S. Legator, L. Molina, J. Meyne   +3 more
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Reproducibility of microbial mutagenicity assays: I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol

, 1984
The Salmonella/microsome test developed by Ames and his coworkers has been widely used in the evaluation of chemicals for genotoxic potential. Although the value of this assay is well recognized, there have been no comprehensive studies on the ...
V. Dunkel, E. Zeiger, D. Brusick, E. McCoy, D. Mcgregor, K. Mortelmans, H. Rosenkranz, V. Simmon   +7 more
semanticscholar   +1 more source

Mutagenicity testing of some medicinal herbs

Journal of Ethnopharmacology, 1987
AbstractExtracts of four brands of a Pakistani local medicine called naswar and six indigenous herbs commonly used as medicine in children were tested for their ability to induce mutations to prototrophy in Salmonella typhimurium tester strains TA98, TA100, TA1535, and TA1537.
A. Nasim, M. M. Malik, S. Riazuddin
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Cytogenetic techniques in mutagenicity testing

Agents and Actions, 1973
Both in vivo and in vitro methodologies have uses as cytogenetic test systems for mutagenicity testing. The in vivo methods are certainly the choice as the primary test system, except perhaps in the case of viruses and some biologicals. When an in vitro method is used anaphase offers some advantages as greater speed and ease of observation, the ...
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Statistical problems in mutagenicity tests

Archives of Toxicology, 1977
Everyone involved in planning and carrying out biological experiments has to concern himself with statistical methods. Thus, descriptive statistics (e. g. calculation of the mean) help to present results briefly and comprehensively and, in addition, statistical test procedures permit decisions to be made even in an uncertain situation.
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Detection of genotoxicity and mutagenicity of chlorthiophos using micronucleus, chromosome aberration, sister chromatid exchange, and Ames tests

Environmental Toxicology, 2015
D. Akyıl, M. Konuk
semanticscholar   +1 more source

Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals

Environmental and Molecular Mutagenesis, 1988
E. Zeiger, B. Anderson, S. Haworth, T. Lawlor, K. Mortelmans   +4 more
semanticscholar   +1 more source