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Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals.
Environmental Mutagenesis, 1987E. Zeiger +5 more
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Granuloma pouch assay for mutagenicity testing
Archives of Toxicology, 1980The Granuloma Pouch Assay (GPA) is an animal model in which mutagenic and carcinogenic effects of a testcompound can be detected in rapidly dividing fibroblasts of a granulation tissue in adult male rats. Growth of this tissue was initiated with a small amount of croton oil at the inside wall of a subcutaneous air pouch on the back of the animals.
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Mutagenicity research and testing in Sweden
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1975A survey is given of Swedish legislation for control of chemicals in the environment. Although no direct legal requirements for mutagenicity testing of chemicals exist at present in Sweden, such requirements can be enforced within the existing laws. Testing and research in chemical mutagenicity are especially performed at the Environmental Toxicology ...
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Microorganisms as test systems for mutagenicity
Archiv f�r Toxikologie, 1971The mutagenic activity of different compounds in bacterial mutagenicity test systems has been investigated. The systems used include back-mutations to prototrophy in auxotrophic strains of Serratia marcescens and forward mutations to galactose prototrophy in a phenotypic galactose negative strain of Escherichia coli.
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Mutagenicity tests with captan and folpet in Drosophila melanogaster.
Mutation research, 1973P. Kramers, A. Knaap
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Mutagenicity – Relevance of Short-Term Tests
Oncology, 1980Short-term tests measuring diverse biological activities of compounds, such as mutagenicity, have been proposed as prescreening methods to determine potential carcinogenicity. High correlations of up to 90% have been found for response in short-term tests versus response in long-term carcinogenicity assays, e.g.
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